Human ARHGEF5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	ARHGEF5
Locus ID	7984
Kit Components	GA105375G1, ARHGEF5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA105375G2, ARHGEF5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA105375G3, ARHGEF5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Disclaimer	These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc.
Reference Data
RefSeq	NM_001002861, NM_005435
Synonyms	DKFZp686N1969; GEF5; guanine nucleotide regulatory protein TIM; P60; P60, TIM, GEF5, TIM1, DKFZp686N1969; Rho guanine nucleotide exchange factor (GEF) 5; rho guanine nucleotide exchange factor 5; TIM; TIM1; transforming immortalized mammary oncogene
Summary	Rho GTPases play a fundamental role in numerous cellular processes initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form a complex with G proteins and stimulate Rho-dependent signals. This protein may be involved in the control of cytoskeletal organization. [provided by RefSeq, Jul 2008]

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