Human PPOX activation kit by CRISPRa
CAT#: GA103703
PPOX CRISPRa kit - CRISPR gene activation of human protoporphyrinogen oxidase
CNY 12,255.00
CNY 3,656.00
CNY 3,990.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | PPOX |
Locus ID | 5498 |
Kit Components | GA103703G1, PPOX gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA103703G2, PPOX gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA103703G3, PPOX gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_000309, NM_001122764, NM_001350128, NM_001350129, NM_001350130, NM_001350131, NM_001365398, NM_001365399, NM_001365400, NM_001365401 |
Synonyms | PPO; V290M; VP |
Summary | This gene encodes the penultimate enzyme of heme biosynthesis, which catalyzes the 6-electron oxidation of protoporphyrinogen IX to form protoporphyrin IX. Mutations in this gene cause variegate porphyria, an autosomal dominant disorder of heme metabolism resulting from a deficiency in protoporphyrinogen oxidase, an enzyme located on the inner mitochondrial membrane. Alternatively spliced transcript variants encoding the same protein have been identified. [provided by RefSeq, Jul 2008] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN401788 | PPOX - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |