Human HLA-DOA activation kit by CRISPRa
CAT#: GA102123
HLA-DOA CRISPRa kit - CRISPR gene activation of human major histocompatibility complex, class II, DO alpha
CNY 12,255.00
货期*
4周
规格
经常一起买 (3)
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | HLA-DOA |
Locus ID | 3111 |
Kit Components | GA102123G1, HLA-DOA gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA102123G2, HLA-DOA gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA102123G3, HLA-DOA gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_002119 |
Synonyms | HLA-DNA; HLA-DZA; HLADZ |
Summary | HLA-DOA belongs to the HLA class II alpha chain paralogues. HLA-DOA forms a heterodimer with HLA-DOB. The heterodimer, HLA-DO, is found in lysosomes in B cells and regulates HLA-DM-mediated peptide loading on MHC class II molecules. In comparison with classical HLA class II molecules, this gene exhibits very little sequence variation, especially at the protein level. [provided by RefSeq, Jul 2008] |
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基因表达相关资源 |
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