Human DPYD activation kit by CRISPRa
CAT#: GA101259
DPYD CRISPRa kit - CRISPR gene activation of human dihydropyrimidine dehydrogenase
CNY 12,255.00
CNY 12,540.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | DPYD |
Locus ID | 1806 |
Kit Components | GA101259G1, DPYD gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA101259G2, DPYD gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA101259G3, DPYD gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Disclaimer | These products are manufactured and supplied by OriGene under license from ERS. The kit is designed based on the best knowledge of CRISPRa SAM technology. The efficiency of the activation can be affected by many factors, including nucleosome occupancy status, chromatin structure and the gene expression level of the target, etc. |
Reference Data | |
RefSeq | NM_000110, NM_001160301 |
Synonyms | DHP; DHPDHASE; DPD |
Summary | The protein encoded by this gene is a pyrimidine catabolic enzyme and the initial and rate-limiting factor in the pathway of uracil and thymidine catabolism. Mutations in this gene result in dihydropyrimidine dehydrogenase deficiency, an error in pyrimidine metabolism associated with thymine-uraciluria and an increased risk of toxicity in cancer patients receiving 5-fluorouracil chemotherapy. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2009] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN416374 | DPYD - KN2.0, Human gene knockout kit via CRISPR, non-homology mediated. |
CNY 8,680.00 |