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Tdp1 (NM_001031657) Rat Tagged ORF Clone Lentiviral Particle
CAT＃: RR211578L4V
- LentiORF®
-
Lenti ORF particles, Tdp1 (GFP-tagged ORF) - Rat tyrosyl-DNA phosphodiesterase 1 (Tdp1), 200ul, >10^7 TU/mL
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CNY 11,970.00
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Specifications
| Product Data | |
| Product Name | Tdp1 (NM_001031657) Rat Tagged ORF Clone Lentiviral Particle |
| Synonyms | MGC112732 |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | NM_001031657 |
| ORF Size | 1827 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(RR211578).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | NM_001031657.1, NP_001026827.1 |
| RefSeq Size | 2096 bp |
| RefSeq ORF | 1830 bp |
| Locus ID | 314380 |
| Gene Summary | DNA repair enzyme that can remove a variety of covalent adducts from DNA through hydrolysis of a 3'-phosphodiester bond, giving rise to DNA with a free 3' phosphate. Catalyzes the hydrolysis of dead-end complexes between DNA and the topoisomerase I active site tyrosine residue. Hydrolyzes 3'-phosphoglycolates on protruding 3' ends on DNA double-strand breaks due to DNA damage by radiation and free radicals. Acts on blunt-ended double-strand DNA breaks and on single-stranded DNA. Has low 3'exonuclease activity and can remove a single nucleoside from the 3'end of DNA and RNA molecules with 3'hydroxyl groups. Has no exonuclease activity towards DNA or RNA with a 3'phosphate (By similarity).[UniProtKB/Swiss-Prot Function] |
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