Cldn15 (NM_001107135) Rat Tagged ORF Clone Lentiviral Particle
CAT#: RR202405L3V
- LentiORF®
Lenti ORF particles, Cldn15 (Myc-DDK-tagged ORF) - Rat claudin 15 (Cldn15), 200ul, >10^7 TU/mL
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CNY 7,410.00
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Specifications
Product Data | |
Product Name | Cldn15 (NM_001107135) Rat Tagged ORF Clone Lentiviral Particle |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_001107135 |
ORF Size | 681 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RR202405).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001107135.2, NP_001100605.1 |
RefSeq Size | 684 bp |
RefSeq ORF | 684 bp |
Locus ID | 304388 |
Gene Summary | Claudins function as major constituents of the tight junction complexes that regulate the permeability of epithelia. While some claudin family members function as impermeable barriers, others mediate the permeability to ions and small molecules. Often, several claudin family members are coexpressed and interact with each other, and this determines the overall permeability. CLDN15 forms tight junctions that mediate the paracellular transport of small monovalent cations along a concentration gradient, due to selective permeability for Na(+), Li(+) and K(+) ions, but selects against Cl(-) ions. Plays an important role in paracellular Na(+) transport in the intestine and in Na(+) homeostasis. Required for normal Na(+)-dependent intestinal nutrient uptake (By similarity).[UniProtKB/Swiss-Prot Function] |
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