Apoptosis inhibitor 5 (API5) (NM_001142930) Human Tagged ORF Clone Lentiviral Particle
CAT#: RC227839L4V
- LentiORF®
Lenti ORF particles, API5 (mGFP-tagged)-Human apoptosis inhibitor 5 (API5), transcript variant 1, 200ul, >10^7 TU/mL
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CNY 9,975.00
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Specifications
Product Data | |
Product Name | Apoptosis inhibitor 5 (API5) (NM_001142930) Human Tagged ORF Clone Lentiviral Particle |
Synonyms | AAC-11; AAC11 |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_001142930 |
ORF Size | 1572 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(RC227839).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_001142930.1 |
RefSeq Size | 3782 bp |
RefSeq ORF | 1575 bp |
Locus ID | 8539 |
Protein Families | Druggable Genome |
MW | 59 kDa |
Gene Summary | This gene encodes an apoptosis inhibitory protein whose expression prevents apoptosis after growth factor deprivation. This protein suppresses the transcription factor E2F1-induced apoptosis and also interacts with, and negatively regulates Acinus, a nuclear factor involved in apoptotic DNA fragmentation. Its depletion enhances the cytotoxic action of the chemotherapeutic drugs. Multiple alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Aug 2011] |
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