Trim14 (NM_029077) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR224121L3V
- LentiORF®
Lenti ORF particles, Trim14 (Myc-DDK-tagged) - Mouse tripartite motif-containing 14 (Trim14), 200ul, >10^7 TU/mL
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CNY 8,835.00
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Specifications
Product Data | |
Product Name | Trim14 (NM_029077) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 5830400N10Rik; pub |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_029077 |
ORF Size | 1320 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR224121).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_029077.4, NP_083353.1 |
RefSeq Size | 3204 bp |
RefSeq ORF | 1323 bp |
Locus ID | 74735 |
Gene Summary | Plays a role in the innate immune defense against viruses. Facilitates the type I IFN response by interacting with MAVS at the outer mitochondria membrane and thereby recruiting NF-kappa-B essential modulator IKBKG/NEMO to the MAVS signalosome, leading to the activation of both the IFN regulatory factor 3/IRF3 and NF-kappa-B pathways. Positively regulates the CGAS-induced type I interferon signaling pathway by stabilizing CGAS and inhibiting its autophagic degradation (PubMed:27666593). Inhibits the transcriptional activity of SPI1 in a dose-dependent manner (PubMed:14592421).[UniProtKB/Swiss-Prot Function] |
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