Ano5 (NM_177694) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR223543L3V
- LentiORF®
Lenti ORF particles, Ano5 (Myc-DDK-tagged) - Mouse anoctamin 5 (Ano5), 200ul, >10^7 TU/mL
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CNY 14,155.00
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规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | Ano5 (NM_177694) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 9330162L24; Gdd1; Tmem16e |
Vector | pLenti-C-Myc-DDK-P2A-Puro |
ACCN | NM_177694 |
ORF Size | 2712 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR223543).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_177694.6, NP_808362.2 |
RefSeq Size | 7785 bp |
RefSeq ORF | 2715 bp |
Locus ID | 233246 |
Gene Summary | This gene encodes a member of the anoctamin family, which in mammals is comprised of 10 members. Anoctamin proteins are proposed to have eight transmembrane domains with both termini facing the cytoplasm and a C-terminal domain of unknown function. While some members have been characterized as calcium-activated chloride channels, this protein is reported to have little anion conductance activity. Elevated levels of this protein were found in dystrophic mice. In humans, mutations of this gene are associated with with musculoskeletal disorders such as myopathies, muscular dystrophy and gnathodiaphyseal dysplasia. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2012] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Deficiency of Anoctamin 5/TMEM16E causes nuclear positioning defect and impairs Ca2+ signaling of differentiated C2C12 myotubes
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The Korean Journal of Physiology & Pharmacology : Official Journal of the Korean Physiological Society and the Korean Society of Pharmacology
,PubMed ID 31680776
[Ano5]
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