Ncstn (NM_021607) Mouse Tagged ORF Clone Lentiviral Particle
CAT#: MR210183L4V
- LentiORF®
Lenti ORF particles, Ncstn (GFP-tagged) - Mouse nicastrin (Ncstn), 200ul, >10^7 TU/mL
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CNY 13,205.00
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Specifications
Product Data | |
Product Name | Ncstn (NM_021607) Mouse Tagged ORF Clone Lentiviral Particle |
Synonyms | 9430068N19Rik; AA727311; Aph2; D1Dau13e; Kiaa0253; mKIAA0253; Nct |
Vector | pLenti-C-mGFP-P2A-Puro |
ACCN | NM_021607 |
ORF Size | 2127 bp |
Sequence Data |
The ORF insert of this clone is exactly the same as(MR210183).
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OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Reference Data | |
RefSeq | NM_021607.2, NP_067620.2 |
RefSeq Size | 2864 bp |
RefSeq ORF | 2127 bp |
Locus ID | 59287 |
Gene Summary | Essential subunit of the gamma-secretase complex, an endoprotease complex that catalyzes the intramembrane cleavage of integral membrane proteins such as Notch receptors and APP (amyloid-beta precursor protein). The gamma-secretase complex plays a role in Notch and Wnt signaling cascades and regulation of downstream processes via its role in processing key regulatory proteins, and by regulating cytosolic CTNNB1 levels.[UniProtKB/Swiss-Prot Function] |
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