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Snapap (BC006744) Mouse Tagged ORF Clone Lentiviral Particle
CAT＃: MR200154L4V
- LentiORF®
-
Lenti ORF particles, Snapap (GFP-tagged) - Mouse SNAP-associated protein (cDNA clone MGC:12076 IMAGE:3708620), 200ul, >10^7 TU/mL
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CNY 7,505.00
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Specifications
| Product Data | |
| Product Name | Snapap (BC006744) Mouse Tagged ORF Clone Lentiviral Particle |
| Synonyms | 25kDa; AA407989; AV026596; Bloc1s7; Snap25bp; Snapap |
| Vector | pLenti-C-mGFP-P2A-Puro |
| ACCN | BC006744 |
| ORF Size | 246 bp |
| Sequence Data |
The ORF insert of this clone is exactly the same as(MR200154).
|
| OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
| Reference Data | |
| RefSeq | BC006744, AAH06744 |
| RefSeq Size | 1858 bp |
| RefSeq ORF | 248 bp |
| Locus ID | 20615 |
| Gene Summary | Component of the BLOC-1 complex, a complex that is required for normal biogenesis of lysosome-related organelles (LRO), such as platelet dense granules and melanosomes. In concert with the AP-3 complex, the BLOC-1 complex is required to target membrane protein cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals. The BLOC-1 complex, in association with SNARE proteins, is also proposed to be involved in neurite extension. Plays a role in intracellular vesicle trafficking and synaptic vesicle recycling. May modulate a step between vesicle priming, fusion and calcium-dependent neurotransmitter release through its ability to potentiate the interaction of synaptotagmin with the SNAREs and the plasma-membrane-associated protein SNAP25. Its phosphorylation state influences exocytotic protein interactions and may regulate synaptic vesicle exocytosis. May also have a role in the mechanisms of SNARE-mediated membrane fusion in non-neuronal cells (PubMed:16760431, PubMed:19546860, PubMed:21998198). As part of the BORC complex may play a role in lysosomes movement and localization at the cell periphery. Associated with the cytosolic face of lysosomes, the BORC complex may recruit ARL8B and couple lysosomes to microtubule plus-end-directed kinesin motor (By similarity).[UniProtKB/Swiss-Prot Function] |
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