LILRB4 (NM_001278429) Human Untagged Clone
CAT#: SC336361
LILRB4 (untagged) - Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 (LILRB4), transcript variant 4
CNY 4,560.00
Product images
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | CD85K; ILT-3; ILT3; LIR-5; LIR5 |
Vector | pCMV6-Entry |
E. coli Selection | Kanamycin (25 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>SC336361 representing NM_001278429.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGGAACAACCCCATGACGAGAAGGACCCAGCCTCCAAGCGGCCACACCCTGTGTGTCTCTTTGTCCTG CCGGCACTGAGGACTCATCCATCTGCACAGCTGGGGCCCCTGGGAGGAGACGCCATGATCCCCACCTTC ACGGCTCTGCTCTGCCTCGGGCCCCTCCCCAAACCCACCCTCTGGGCTGAGCCAGGCTCTGTGATCAGC TGGGGGAACTCTGTGACCATCTGGTGTCAGGGGACCCTGGAGGCTCGGGAGTACCGTCTGGATAAAGAG GAAAGCCCAGCACCCTGGGACAGACAGAACCCACTGGAGCCCAAGAACAAGGCCAGATTCTCCATCCCA TCCATGACAGAGGACTATGCAGGGAGATACCGCTGTTACTATCGCAGCCCTGTAGGCTGGTCACAGCCC AGTGACCCCCTGGAGCTGGTGATGACAGGAGCCTACAGTAAACCCACCCTTTCAGCCCTGCCGAGTCCT CTTGTGACCTCAGGAAAGAGCGTGACCCTGCTGTGTCAGTCACGGAGCCCAATGGACACTTTTCTTCTG ATCAAGGAGCGGGCAGCCCATCCCCTACTGCATCTGAGATCAGAGCACGGAGCTCAGCAGCACCAGGCT GAATTCCCCATGAGTCCTGTGACCTCAGTGCACGGGGGGACCTACAGGTGCTTCAGCTCACACGGCTTC TCCCACTACCTGCTGTCACACCCCAGTGACCCCCTGGAGCTCATAGTCTCAGGATCCTTGGAGGGTCCC AGGCCCTCACCCACAAGGTCCGTCTCAACAGCTGCAGGCCCTGAGGACCAGCCCCTCATGCCTACAGGG TCAGTCCCCCACAGTGGTCTGAGAAGGCACTGGGAGGTACTGATCGGGGTCTTGGTGGTCTCCATCCTG CTTCTCTCCCTCCTCCTCTTCCTCCTCCTCCAACACTGGCGTCAGGGAAAACACAGGACATTGGCCCAG AGACAGGCTGATTTCCAACGTCCTCCAGGGGCTGCCGAGCCAGAGCCCAAGGACGGGGGCCTACAGAGG AGGTCCAGCCCAGCTGCTGACGTCCAGGGAGAAAACTTCTCAGGTGCTGCCGTGAAGAACACACAGCCT GAGGACGGGGTGGAAATGGACACTCGGCAGAGCCCACACGATGAAGACCCCCAGGCAGTGACGTATGCC AAGGTGAAACACTCCAGACCTAGGAGAGAAATGGCCTCTCCTCCCTCCCCACTGTCTGGGGAATTCCTG GACACAAAGGACAGACAGGCAGAAGAGGACAGACAGATGGACACTGAGGCTGCTGCATCTGAAGCCCCC CAGGATGTGACCTACGCCCGGCTGCACAGCTTTACCCTCAGACAGAAGGCAACTGAGCCTCCTCCATCC CAGGAAGGGGCCTCTCCAGCTGAGCCCAGTGTCTATGCCACTCTGGCCATCCACTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
Restriction Sites | SgfI-MluI |
ACCN | NM_001278429 |
Insert Size | 1437 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | NM_001278429.3 |
RefSeq Size | 3869 bp |
RefSeq ORF | 1437 bp |
Locus ID | 11006 |
UniProt ID | Q8NHJ6 |
Protein Families | Transmembrane |
MW | 52.5 kDa |
Gene Summary | This gene is a member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein belongs to the subfamily B class of LIR receptors which contain two or four extracellular immunoglobulin domains, a transmembrane domain, and two to four cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs). The receptor is expressed on immune cells where it binds to MHC class I molecules on antigen-presenting cells and transduces a negative signal that inhibits stimulation of an immune response. The receptor can also function in antigen capture and presentation. It is thought to control inflammatory responses and cytotoxicity to help focus the immune response and limit autoreactivity. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Transcript Variant: This variant (4) lacks an in-frame exon in the 5' coding region, uses an alternate in-frame splice site in the central coding region, and initiates translation at an upstream start codon, compared to variant 1. The encoded isoform (4) is longer and contains a distinct N-terminus, compared to isoform 1. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. |
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Other Versions
SKU | Description | Size | Price |
---|---|---|---|
RC238467 | LILRB4 (myc-DDK-tagged) - Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 (LILRB4), transcript variant 4 |
CNY 3,990.00 |
|
RG238467 | LILRB4 (tGFP-tagged) - Human leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 4 (LILRB4), transcript variant 4 |
CNY 4,370.00 |