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Nesprin3 (SYNE3) (NM_152592) Human Untagged Clone
CAT＃: SC306453
SYNE3 (untagged)-Human chromosome 14 open reading frame 49 (C14orf49)
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | C14orf49; C14orf139; KASH3; LINC00341; NCRNA00341; Nesp3; NET53 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>SC306453 representing NM_152592.
Blue=Insert sequence Red=Cloning site Green=Tag(s) GCTCGTTTAGTGAACCGTCAGAATTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTG GATCCGGTACCGAGGAGATCTGCCGCCGCGATCGCC ATGACTCAGCAGCCCCAGGACGACTTTGACAGGAGCGTGGAGGATGCCCAGGCATGGATGAAGGCTGTG CAGGACCAGCTGCAGGTCAATGACAACACGCAGGGACCCCGCGCGGCCCTGGAGGCCAGGCTGTGGGAG ACCGAGAAAATATGCCAGCTGGAGCCCGAGGGGCGTGTGAGGGTGGACCTCGTGCTACGGATGGCTGAA GCCCTCTTGGCATGCTGCCCTGGGGACCAGAAGCCCGGGATCCTGGCCCGGCTGAAGGACATCAAGGCC CAATGGGAGGAGACAGTCACCTACATGACTCACTGTCACAGCCGCATCGAGTGGGTGTGGCTGCACTGG AGCGAGTACCTGCTGGCCCGAGATGAGTTCTACCGCTGGTTCCAGAAGATGATGGTCACACTGGAGCCC CACATCGAGCTCCAGCTGGGCCTGAAGGAGAAGCAGTGGCAGCTGAGCCACGCCCAGGTGCTGCTGCAC AACGTGGACAACCAGGCGGTGCTCCTGGACCGGCTGCTGGAGGAGGCAGCCTCCCTGTTCAACAGGATC GGGGACCCCAGCGTGGACGAAGATGCCCAGAAGAGAATGAAGGCTGAGTACGATGCAGTGAAGGCCAAG GCCCAGAAGCGTGTAGATCTGCTGGAGCAGGTGGCCCGGGAGCATGAGGAGTACCAGGCAGGTGTGGAC GAGTTCCAACTGTGGCTGAAGGCGGTGGTGGAGAAGGTGAATGGCTGCCTGGGGCGGAACTGCAAGCTG CCCATCACGCAGCGCCTCTCCACACTGCAGGACATTGCCAAAGATTTTCCCAGGGGCGAGGAGTCTCTG GAGACGCTGGAGGAGCAGTCTGCGGGTGTCATTCGGAACACCTCTCCTTTGGGTGCAGAGAAGATCACC GGAGAACTGGAAGAGATGAGGAAAGTTCTGGAGAAGCTGCGCGCCCTCTGGGAGGAGGAGGAGGAGCGG CTGCGGGGCCTGCTCCGGTCCAGGGGAGCCTGGGAGCAGCAGATTAAGCAGCTGGAGGCTGAGCTCAGT GAGTTCAGGATGGTCCTGCAGAGGCTGGCCCAGGAGGGCCTGCAGCCTGCGGCGAAAGCGGGGACCGAG GACGAGCTGGTGGCACACTGGAGACGCTACTCGGCAACACGGGCGGCGCTGGCCTCGGAGGAGCCCCGG GTGGACCGGCTGCAAGCCCAGCTGAAGGAGCTCATCGTCTTCCCTCACAACCTGAAGCCACTCTCTGAT AGTGTCATCGCTACCATCCAGGAGTATCAGAGCCTGAAGGTGAAGAGCGCGAGGCTGCGCAATGCCGCG GCGGTGGAGCTGTGGCAGCATTTCCAGCGGCCTCTGCAGGATCTGCAGCTGTGGAAGGCCCTGGCCCAG CGGCTCTTGGAGGTCACTGCCAGCCTGCCGGACCTGCCTTCCCTTCACACCTTCCTGCCCCAGATCGAG GCAGCCCTGATGGAAAGCTCCCGCCTGAAAGAGCTGCTGACGATGCTGCAGCTGAAGAAAGACCTCCTG ATTGGCATCTTTGGCCAGGAGAGAGCCACGGCACTCCTGGAGCAGGTGGCAGGTTCCATGAGGGACAGA GACCTGCTGCATAACAGCCTCCTGCAGAGGAAAAGCAAACTGCAGAGCCTGCTCGCTCAGCACAAAGAC TTTGGAGCAGCTTTTGAGCCCCTGCAGAGGAAGCTCTTGGACCTCCAGGTCAGGGTCCAAGCCGAGAAG GGGCTTCAGCGGGACCTTCCTGGAAAACAGGCCCAGCTCTCAAGGTTGCAGGGGCTGCAGGAAGAGGGG CTGGACTTGGGGGCACAGATGGAGGCTGCAAGGCCTCTGGTCCAGGAGAACCCCAACCACCAGCACAAA ATGGACCAGCTTTCCTCCGACTTCCAGGCCCTGCAGAGGTCTCTGGAGGACCTTGTGGACAGGTGTCGG CAGAGTGTGCAGGAGCACTGCACCTTCAGCCACCAGCTGCTGGAGCTGCGGCAGTGGATCGTTGTGACC ACGCAAAAGCTGGAGGCACACCGGGGAGAGGCGGGCCCGGGGGATGCCGAGTCCCAAGAGGCCGAGTTT GAGAGGCTGGTGGCAGAATTCCCGGAGAAGGAGGCCCAGCTGTCCCTGGTGGAAGCGCAGGGCTGGCTG GTGATGGAGAAGTCTTCTCCGGAGGGTGCTGCCGTGGTGCAGGAGGAGCTCAGGGAGCTGGCAGAGTCG TGGCGGGCCTTGAGGCTGCTGGAAGAAAGTCTGCTGAGCCTCATCAGAAACTGGCATCTGCAGAGGATG GAAGTGGATTCGGGGAAGAAAATGGTTTTCACCAACAACATCCCAAAGTCAGGATTTCTCATCAATCCC ATGGATCCTATTCCCAGGCATCGTCGACGCGCAAATCTTCTACAGGAAGAAGAAGGGAGCCATGAAGAT TTCTCCCAGCTCCTGAGGAACTTTGGGCAGTGGTTGCAGGTGGAAAACTCCAAGCTGGTTAGAATCATC GCAATGAGAACTTCTACAGCTGAGGACTTGAGGACCAGAAAATCGAAGCTGCAGGAGCTGGAGGCTCGG GTGCCAGAAGGTCAGCATCTCTTTGAGAACCTCCTTCGTCTCGGGCCAGCAAGGGGGACCTCGGATGAG CTGGAAGATCTGCGCTACCAGTGGATGCTGTACAAGTCCAAGCTGAAGGACTCTGGCCACCTGCTGACA CAAAGTTCTCCAGGGGAGCCGACTGGATTCCAAAAGACTCGGCGGTGGCGAGGACTGGGCTCCCTCTTC CGGAGGGCGTGCTGTGTGGCGCTCCCACTGCAGCTGCTTCTGCTGCTGTTCCTCCTCCTGCTGTTCCTG CTCCCAATCAGGGAAGAGGACCGCAGCTGCACCCTGGCCAACAACTTCGCCCGCTCCTTCACGCTCATG CTGCGCTACAATGGCCCACCACCCACCTAA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGAT TACAAGGATGACGACGATAAGGTTTAAACGGCCGGC |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_152592 |
| Insert Size | 2928 bp |
| OTI Disclaimer | Due to the inherent nature of this plasmid, standard methods to replicate additional amounts of DNA in E. coli are highly likely to result in mutations and/or rearrangements. Therefore, OriGene does not guarantee the capability to replicate this plasmid DNA. Additional amounts of DNA can be purchased from OriGene with batch-specific, full-sequence verification at a reduced cost. Please contact our customer care team at custsupport@origene.com or by calling 301.340.3188 option 3 for pricing and delivery. The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_152592.3 |
| RefSeq Size | 3277 bp |
| RefSeq ORF | 2928 bp |
| Locus ID | 161176 |
| UniProt ID | Q6ZMZ3 |
| Protein Families | Transmembrane |
| MW | 112.2 kDa |
| Gene Summary | As a component of the LINC (LInker of Nucleoskeleton and Cytoskeleton) complex involved in the connection between the nuclear lamina and the cytoskeleton. The nucleocytoplasmic interactions established by the LINC complex play an important role in the transmission of mechanical forces across the nuclear envelope and in nuclear movement and positioning. Probable anchoring protein which tethers the nucleus to the cytoskeleton by binding PLEC which can associate with the intermediate filament system. Plays a role in the regulation of aortic epithelial cell morphology, and is required for flow-induced centrosome polarization and directional migration in aortic endothelial cells.[UniProtKB/Swiss-Prot Function] |
Documents
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| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC217809 | SYNE3 (Myc-DDK-tagged)-Human chromosome 14 open reading frame 49 (C14orf49) |
CNY 10,712.00 |
|
| RC217809L3 | Lenti ORF clone of Human chromosome 14 open reading frame 49 (C14orf49), Myc-DDK-tagged |
CNY 9,030.00 |
|
| RC217809L4 | Lenti ORF clone of Human chromosome 14 open reading frame 49 (C14orf49), mGFP tagged |
CNY 9,030.00 |
|
| RG217809 | SYNE3 (tGFP-tagged) - Human chromosome 14 open reading frame 49 (C14orf49) |
CNY 12,312.00 |
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