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RNF158 (SH3RF2) (NM_152550) Human Untagged Clone
CAT＃: SC306436
SH3RF2 (untagged)-Human SH3 domain containing ring finger 2 (SH3RF2)
CNY 5,880.00
CNY 7,220.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | HEPP1; POSHER; PPP1R39; RNF158 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_152550 |
| Insert Size | 2190 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| OTI Annotation | This TrueClone is provided through our Custom Cloning Process that includes sub-cloning into OriGene's pCMV6 vector and full sequencing to provide a non-variant match to the expected reference without frameshifts, and is delivered as lyophilized plasmid DNA. |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_152550.3 |
| RefSeq Size | 3043 bp |
| RefSeq ORF | 2190 bp |
| Locus ID | 153769 |
| UniProt ID | Q8TEC5 |
| MW | 79.3 kDa |
| Gene Summary | Has E3 ubiquitin-protein ligase activity (PubMed:24130170). Acts as an anti-apoptotic regulator of the JNK pathway by ubiquitinating and promoting the degradation of SH3RF1, a scaffold protein that is required for pro-apoptotic JNK activation (PubMed:22128169). Facilitates TNF-alpha-mediated recruitment of adapter proteins TRADD and RIPK1 to TNFRSF1A and regulates PAK4 protein stability via inhibition of its ubiquitin-mediated proteasomal degradation (PubMed:24130170). Inhibits PPP1CA phosphatase activity (PubMed:19945436, PubMed:19389623).[UniProtKB/Swiss-Prot Function] |
Documents
| Product Manuals |
| FAQs |
| SDS |
Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC213552 | SH3RF2 (Myc-DDK-tagged)-Human SH3 domain containing ring finger 2 (SH3RF2) |
CNY 5,344.00 |
|
| RC213552L3 | Lenti ORF clone of Human SH3 domain containing ring finger 2 (SH3RF2), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC213552L4 | Lenti ORF clone of Human SH3 domain containing ring finger 2 (SH3RF2), mGFP tagged |
CNY 5,890.00 |
|
| RG213552 | SH3RF2 (tGFP-tagged) - Human SH3 domain containing ring finger 2 (SH3RF2) |
CNY 6,944.00 |
