MUM1 (IRF4) (BC015752) Human Untagged Clone
CAT#: SC122246
IRF4 (untagged)-Human interferon regulatory factor 4 (cDNA clone MGC:23069 IMAGE:4861223), complete cds
CNY 5,528.00
货期*
现货
规格
Cited in 1 publication. |
Product images
经常一起买 (4)
Specifications
Product Data | |
Type | Human Untagged Clone |
Tag | Tag Free |
Synonyms | interferon regulatory factor 4; LSIRF; multiple myeloma oncogene 1; MUM1; OTTHUMP00000017905 |
Vector | pCMV6-XL5 |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | None |
Sequence Data |
>OriGene sequence for BC015752 edited
CTCCGAGTCCAGGGCGAGTGCAGAGCAGAGCGGGCGGAGGACCCCGGGCGCGGGCGCGGA CGGCACGCGGGGCATGAACCTGGAGGGCGGCGGCCGAGGCGGAGAGTTCGGCATGAGCGC GGTGAGCTGCGGCAACGGGAAGCTCCGCCAGTGGCTGATCGACCAGATCGACAGCGGCAA GTACCCCGGGCTGGTGTGGGAGAACGAGGAGAAGAGCATCTTCCGCATCCCCTGGAAGCA CGCGGGCAAGCAGGACTACAACCGCGAGGAGGACGCCGCGCTCTTCAAGGCTTGGGCACT GTTTAAAGGAAAGTTCCGAGAAGGCATCGACAAGCCGGACCCTCCCACCTGGAAGACGCG CCTGCGGTGCGCTTTGAACAAGAGCAATGACTTTGAGGAACTGGTTGAGCGGAGCCAGCT GGACATCTCAGACCCGTACAAAGTGTACAGGATTGTTCCTGAGGGAGCCAAAAAAGGAGC CAAGCAGCTCACCTTGGAGGACCCGCAGATGTCCATGAGCCACCCCTACACCATGACAAC GCCTTACCCTTCGCTCCCAGCCCAGCAGGTTCACAACTACATGATGCCACCCCTCGACCG AAGCTGGAGGGACTACGTCCCGGATCAGCCACACCCGGAAATCCCGTACCAATGTCCCAT GACGTTTGGACCCCGCGGCCACCACTGGCAAGGCCCAGCTTGTGAAAATGGTTGCCAGGT GACAGGAACCTTTTATGCTTGTGCCCCACCTGAGTCCCAGGCTCCCGGAGTCCCCACAGA GCCAAGCATAAGGTCTGCCGAAGCCTTGGCGTTCTCAGACTGCCGGCTGCACATCTGCCT GTACTACCGGGAAATCCTCGTGAAGGAGCTGACCACGTCCAGCCCCGAGGGCTGCCGGAT CTCCCATGGACATACGTATGACGCCAGCAACCTGGACCAGGTCCTGTTCCCCTACCCAGA GGACAATGGCCAGAGGAAAAACATTGAGAAGCTGCTGAGCCACCTGGAGAGGGGCGTGGT CCTCTGGATGGCCCCCGACGGGCTCTATGCGAAAAGACTGTGCCAGAGCAGGATCTACTG GGACGGGCCCCTGGCGCTGTGCAACGACCGGCCCAACAAACTGGAGAGAGACCAGACCTG CAAGCTCTTTGACACACAGCAGTTCTTGTCAGAGCTGCAAGCGTTTGCTCACCACGGCCG CTCCCTGCCAAGATTCCAGGTGACTCTATGCTTTGGAGAGGAGTTTCCAGACCCTCAGAG GCAAAGAAAGCTCATCACAGCTCACGTAGAACCTCTGCTAGCCAGACAACTATATTATTT TGCTCAACAAAACAGTGGACATTTCCTGAGGGGCTACGATTTACCAGAACACATCAGCAA TCCAGAAGATTACCACAGATCTATCCGCCATTCCTCTATTCAAGAATGAAAAATGTCAAG ATGAGTGGTTTTCTTTTTCCTTTTTTTTTTTTTTTTGATACGGAGATACGGGGTCTTGCT CTGTCTCCCAGGCTGGAGTGCAGTGACACAATCTCAGCTCACTGTGACCTCCGCCTCCTG GGTTCAAGAGACTCTCCTGCCTCAGCCTCCCTGGTAGCTGGGATTACAGGTGTGAGCCAC TGCACCCACCCAAGACAAGTGATTTTCATTGTAAATATTTGACTTTAGTGAAAGCGTCCA ATTGACTGCCCTCTTACTGTTTTGAGGAACTCAGAAGTGGAGATTTCAGTTCAGCGGTTG AGGAGAATTGCGGCGAGACAAGCATGGAAAATCAGTGACATCTGATTGGCAGATGAGCTT ATTTCAAAAGGAAGGGTGGCTTTGCATTTCTTGTGTTCTATAGACTGCCATCATTGATGA TCACTGTGAAAATTGACCAAGTGATGTGTTTACATTTACTGAAATGCGCTCTTTAATTTG TTGTAGATTAGGTCTTGCTGGAAGACAGAGAAAACTTGCCTTTCAGTATTGACACTGACT AGAGTGATGACTGCTTGTAGGTATGTCTGTGCCATTTCTCAGGGAAGTAAGATGTAAATT GAAGAAGCCTCACACGTAAAAGAAATGTATTAACGTATGTAGGAGCTGCAGTTCTTGTGG AAGACACTTGCTGAGTGAAGGAAATGAATCTTTGACTGAAGCCGTGCCTGTAGCCTTGGG GAGGCCCATCCCCCACCTGCCAGCGGTTTCCTGGTGTGGGTCCCTCTGCTCCCTCTGAAA AAAAAAAAAAAAAAA >OriGene 5' read for BC015752 unedited
NNNNCCAGTTCACATTTGTATACGACTCATATAGGCGGCACGCGAATTCGCACGAGGCTC CGAGTCCAGGCGAGTGCAGAGCAGAGCGGGCGGAGGACCCCGGGCGCGGGCGCGGACGGC ACGCGGGGCATGAACCTGGAGGGCGGCGGCCGAGGCGGAGAGTTCGGCATGAGCGCGGTG AGCTGCGGCAACGGGAAGCTCCGCCAGTGGCTGATCGACCAGATCGACAGCGGCAAGTAC CCCGGGCTGGTGTGGGAGAACGAGGAGAAGAGCATCTTCCGCATCCCCTGGAAGCACGCG GGCAAGCAGGACTACAACCGCGAGGAGGACGCCGCGCTCTTCAAGGCTTGGGCACTGTTT AAAAGAAAGTTCCGAGAAGGCATCGACAAGCCGGACCCTCCCACCTGGAAGACGCGCCTG CGGTGCGCTTTGAACAAGAGCAATGACTTTGAGGAACTGGTTGAGCGGAGCCAGCTGGAC ATCTCAGACCCGTACAAAGTGTACAGGATTGTTCCTGAGGGAGCCAAAAAAGGAGCCAAG CAGCTCACCTTGGAGGACCCGCAGATGTCCATGAGCCACCCCTACACCATGACAACGCCT TACCCTTCGCTCCCAGCCCAGCAGGTTCACAACTACATGATGCCACCCCTCGACCGAAGC TGGAGGGACTACGTCCCGGATCAGCCACACCCGGGAATCCCGTACCAATGTCCCATGACG TTTGGACCCCGCGGCCACCACTGGNCAGGCCCAGCTTGTGAAAATGGTTGCCAGGTGACA GGAACCTTTTATAGCTGTGCCCCACCTGAGTCCCCAGCTCCCGGAGTCCCCACAGAGCCC AGCATAAGGTCTGCCGAAGCTC |
Restriction Sites | Please inquire |
ACCN | BC015752 |
Insert Size | 2235 bp |
OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
Reference Data | |
RefSeq | BC015752.1, AAH15752.1 |
RefSeq Size | 2235 bp |
Locus ID | 3662 |
Protein Families | Druggable Genome, Transcription Factors |
Gene Summary | The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Aug 2010] |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Bromodomain inhibition of the transcriptional coactivators CBP/EP300 as a therapeutic strategy to target the IRF4 network in multiple myeloma
,Conery, AR;Centore, RC;Neiss, A;Keller, PJ;Joshi, S;Spillane, KL;Sandy, P;Hatton, C;Pardo, E;Zawadzke, L;Bommi-Reddy, A;Gascoigne, KE;Bryant, BM;Mertz, JA;Sims, RJ;,
Elife
,PubMed ID 26731516
[IRF4]
|
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