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TWEAKR (TNFRSF12A) (NM_016639) Human Untagged Clone
CAT＃: SC114174
TNFRSF12A (untagged)-Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A)
CNY 1,200.00
CNY 2,950.00
| Cited in 2 publications. |
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | CD266; FN14; TWEAKR |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF sequence for NM_016639 edited
ATGGCTCGGGGCTCGCTGCGCCGGTTGCTGCGGCTCCTCGTGCTGGGGCTCTGGCTGGCG TTGCTGCGCTCCGTGGCCGGGGAGCAAGCGCCAGGCACCGCCCCCTGCTCCCGCGGCAGC TCCTGGAGCGCGGACCTGGACAAGTGCATGGACTGCGCGTCTTGCAGGGCGCGACCGCAC AGCGACTTCTGCCTGGGCTGCGCTGCAGCACCTCCTGCCCCCTTCCGGCTGCTTTGGCCC ATCCTTGGGGGCGCTCTGAGCCTGACCTTCGTGCTGGGGCTGCTTTCTGGCTTTTTGGTC TGGAGACGATGCCGCAGGAGAGAGAAGTTCACCACCCCCATAGAGGAGACCGGCGGAGAG GGCTGCCCAGCTGTGGCGCTGATCCAGTGA >OriGene 5' read for NM_016639 unedited
CCGAATAGGNATCCGACTTACTATAGGCGGCCGCGCAATTCGCACGAGGGACGTGCACTA TGGCTCGGGGCTCGCTGCGCCGGTTGCTGCGGCTCCTCGTGCTGGGGCTCTGGCTGGCGT TGCTGCGCTCCGTGGCCGGGGAGCAAGCGCCAGGCACCGCCCCCTGCTCCCGCGGCAGCT CCTGGAGCGCGGACCTGGACAAGTGCATGGACTGCGCGTCTTGCAGGGCGCGACCGCACA GCGACTTCTGCCTGGGCTGCGCTGCAGCACCTCCTGCCCCCTTCCGGCTGCTTTGGCCCA TCCTTGGGGGCGCTCTGAGCCTGACCTTCGTGCTGGGGCTGCTTTCTGGCTTTTTGGTCT GGAGACGATGCCGCAGGAGAGAGAAGTTCACCACCCCCATAGAGGAGACCGGCGGACAGG GCTGCCCAGCTGTGGCGCTGATCCAGTGACAATGTGCCCCCTGCCAGCCGGGACCTCGCC CACTCATCATTCATTCATCCATTCTAGAGCCAGTCTCTGCCTCCCAGACGCGGCGGGAGC CAAGCTCCTCCAACCACAAGGGGGGTGGGGGGCGGTGAATCACCTCTGAGGCCTGNGCCC AGGGTTCAGGGGAACCTTCCAAGGTGTCTGGTTGCCCTGCCTCTGGCTCCAGAACAGAAA GGGAGCCTCACGCTGGCTCACACAAAACAGCTGACACTGACTAANGAACTGCAGCATTTG CACAGGGGAGGGGGGTGCCCTTCTTCCTAGAGGCCCTGGGGGCCANGCTGACTTGTGGGG CAGACTTGACACTANGCCCCACTCACTCAGATGTTCTGAAATTCCACCACGGGGTCACCC TGTGGGGTTAGGGACCTATTTNTTACACTAGGGGGCCTGCCCACTNAGAAGCCTGCCCCT AGAAACAGACCCCCCAACTCCCCAAGCGGGGAGGAGATATTATTTTGGGGAAAGCTTGGA GGGAGGGAGAATTATTATAAAGATCCTT |
| Restriction Sites | NotI-NotI |
| ACCN | NM_016639 |
| Insert Size | 1000 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_016639.1, NP_057723.1 |
| RefSeq Size | 998 bp |
| RefSeq ORF | 390 bp |
| Locus ID | 51330 |
| UniProt ID | Q9NP84 |
| Protein Families | Druggable Genome, Transmembrane |
| Protein Pathways | Cytokine-cytokine receptor interaction |
| Gene Summary | Receptor for TNFSF12/TWEAK. Weak inducer of apoptosis in some cell types. Promotes angiogenesis and the proliferation of endothelial cells. May modulate cellular adhesion to matrix proteins.[UniProtKB/Swiss-Prot Function] |
Citations (2)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
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Overexpression of Fn14 promotes androgen-independent prostate cancer progression through MMP-9 and correlates with poor treatment outcome
,Mingguo Huang, Shintaro Narita, Norihiko Tsuchiya, Zhiyong Ma, Kazuyuki Numakura, Takashi Obara, Hiroshi Tsuruta, Mitsuru Saito, Takamitsu Inoue, Yohei Horikawa, Shigeru Satoh, and Tomonori Habuchi,
Carcinogenesis, Nov 2011; 32: 1589 - 1596.
[TNFRSF12A]
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A Previously Unrecognized Protein-Protein Interaction between TWEAK and CD163: Potential Biological Implications
,LC Bover, M Cardo-Vila, A Kuniyasu, J Sun, R Rangel, M Takeya, BB Aggarwal, W Arap, and R Pasqualini,
J Immunol. 2007 Jun 15;178(12):8183-94
[TNFRSF12A]
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Documents
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC201041 | TNFRSF12A (Myc-DDK-tagged)-Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A) |
CNY 1,200.00 |
|
| RC201041L1 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC201041L2 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A), mGFP tagged |
CNY 5,890.00 |
|
| RC201041L3 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A), Myc-DDK-tagged |
CNY 3,600.00 |
|
| RC201041L4 | Lenti ORF clone of Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A), mGFP tagged |
CNY 3,600.00 |
|
| RG201041 | TNFRSF12A (tGFP-tagged) - Human tumor necrosis factor receptor superfamily, member 12A (TNFRSF12A) |
CNY 2,800.00 |
