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IFIT5 (NM_012420) Human Untagged Clone
CAT＃: SC111218
IFIT5 (untagged)-Human interferon-induced protein with tetratricopeptide repeats 5 (IFIT5)
CNY 3,656.00
Product images
Specifications
| Product Data | |
| Type | Human Untagged Clone |
| Tag | Tag Free |
| Synonyms | ISG58; P58; RI58 |
| Vector | pCMV6-XL5 |
| E. coli Selection | Ampicillin (100 ug/mL) |
| Mammalian Cell Selection | None |
| Sequence Data |
>OriGene ORF within SC111218 sequence for NM_012420 edited (data generated by NextGen Sequencing)
ATGAGTGAAATTCGTAAGGACACCTTGAAGGCCATTCTGTTGGAGTTAGAATGTCATTTT ACATGGAATTTACTTAAGGAAGACATTGATCTGTTTGAGGTAGAAGATACAATTGGGCAA CAGCTTGAATTTCTTACCACAAAATCTAGACTTGCTCTTTATAACCTATTGGCCTATGTG AAACACCTAAAAGGCCAAAATAAAGACGCCCTTGAGTGCTTGGAACAAGCAGAAGAAATA ATCCAGCAAGAACACTCAGACAAAGAAGAAGTACGAAGCCTGGTCACTTGGGGAAACTAT GCCTGGGTGTATTATCACATGGACCAGCTTGAAGAAGCTCAGAAGTATACAGGTAAGATA GGGAATGTCTGTAAGAAATTGTCCAGTCCTTCTAACTACAAGTTGGAGTGTCCTGAGACT GACTGTGAGAAAGGCTGGGCACTCTTGAAATTTGGAGGAAAGTATTATCAAAAGGCTAAA GCGGCTTTTGAGAAGGCTCTGGAAGTGGAGCCTGACAATCCAGAATTTAACATCGGCTAT GCTATCACAGTGTATCGGCTGGATGATTCTGATAGAGAAGGGTCTGTAAAGAGCTTTTCT CTGGGGCCTTTGAGAAAGGCTGTTACCCTGAACCCAGATAACAGCTATATTAAGGTTTTT CTGGCACTGAAGCTTCAAGATGTACATGCAGAAGCTGAAGGGGAAAAGTATATTGAAGAA ATCCTGGACCAAATATCATCCCAGCCTTACGTCCTTCGTTATGCAGCCAAGTTCTATAGG AGAAAAAATTCCTGGAACAAAGCTCTCGAACTTTTAAAAAAGGCCTTGGAGGTGACACCA ACTTCTTCTTTCCTGCATCACCAGATGGGACTTTGCTACAGGGCACAAATGATCCAAATC AAGAAGGCCACACACAACAGACCTAAAGGAAAGGATAAACTAAAGGTTGATGAGCTGATT TCATCTGCTATATTTCATTTCAAAGCAGCCATGGAACGAGACTCTATGTTTGCATTTGCC TACACAGACCTGGCCAACATGTACGCTGAAGGAGGCCAGTATAGCAATGCTGAGGACATT TTCCGGAAAGCTCTTCGTCTGGAGAACATAACCGATGATCACAAACATCAGATCCATTAC CACTATGGCCGCTTTCAGGAATTTCACCGTAAATCAGAAAATACTGCCATCCATCATTAT TTAGAAGCCTTAAAGGTCAAAGACAGATCACCCCTTCGCACCAAACTGACAAGTGCTCTG AAGAAATTGTCTACCAAGAGACTTTGTCACAATGCTTTAGATGTGCAGAGTTTAAGTGCC CTAGGGTTTGTTTACAAGCTGGAAGGAGAAAAGAGGCAAGCTGCTGAGTACTATGAGAAG GCACAAAAGATAGATCCAGAAAATGCAGAATTCCTGACTGCTCTCTGTGAGCTCCGACTT TCCATTTAA Clone variation with respect to NM_012420.2 >OriGene 5' read for NM_012420 unedited
TACGACTCCTATGGGGCGGCCGCGATTCGGCACGAGGATTCAATCTCCAGTTTCCTGTTC TTGCTGGGGCTGGGGTCTCTCCTTTAACAAAGACACGCCGCGCGGCCGAGTCCAGGGGCT GCAGAGGCCTGGCGCGCGCACGCGCACGCGCACGCCCACCGCGCGGCTTCCCGCGGTCCC CGGTGCTGAGGAGAGAGCGATCCGAGGGACTGCGCCGCCCGGACGGCCTGCAGAGCGCTG CCATCATGAGTGAAATTCGTAAGGACACCTTGAAGGCCATTCTGTTGGAGTTAGAATGTC ATTTTACATGGAATTTACTTAAGGAAGACATTGATCTGTTTGAGGTAGAAGATACAATTG GGCAACAGCTTGAATTTCTTACCACAAAATCTAGACTTGCTCTTTATAACCTATTGGCCT ATGTGAAACACCTAAAAGGCCAAAATAAAGACGCCCTTGAGTGCTTGGAACAAGCAGAAG AAATAATCCAGCAAGAACACTCAGACAAAGAAGAAGTACGAAGCCTGGTCACTTGGGGAA ACTATGCCTGGGTGTATTATCACATGGACCAGCTTGAAGAAGCTCAGAAGTATACAGGTA AGATAGGGAATGTCTGTAAGAAATTGTCCAGTCCTTCTAACNTACAAGTTGGAGTGTCCT GAGACTGACTGTGAGAAAGGGCTGGGCACTCTTGAAATTTGGAGGAAAGTATTATCAAAA GGCTAAAGCGGCTNTTGAGAAGCTCTGGNAGTGGAGCCTGACATCCAGATNTACATCGGC TTGCTATCACAGTGTATCGGCTGGATGATTCTGATAGAGAGGGTCTGTAAGAGCTTTCTC TGGGGCCTTGAGAAGGCTGGTACCTGACCAGATACAGTTANTTAGGTTTTCTGCCTGAGC TTCAAAGTACTGCANACTGAGGGGAAAGTTATGAGAATCTGACAATTCATCCAACTTG >OriGene 3' read for NM_012420 unedited
TTTTTTTTTTTTTTTTTAAGTAAAACAAAGNATTTTAAAAATTAATACGTGAGAAACACT GCAGTATATATGTATGTCTGATTACGCATAGAAAAAAATCTGGAAGTTTACATATCAAAT TATAAGTTATAAGTTTACCTTGAGGGTGTGGAACTGTGGTAGGGTGAGAGGACTGCTCTC ATTTTTAAATTCACATACTTTTGTAATTTTTTTTTGAAATTTACAGTGAGAATTCATTAT TTTTATAATAATCAAACCATAATAGAAATTTTAAAGATGATAAAAAACAAAAAGTAAAAC ACACACACATACATAATAATTTTAAGAGTTACATTGGAGGAATGGAGAATTAAATCACAT GGTACTTTTCCACTAATACTGTGATGGTACATAATTGTGTAGTCGGTAATCAAAGAAACT ACATTAGAGAAGCCACATTAAGTAACATCCGAATTAAAAAGTCCCCTGGGATAAGAGCCC TCAAGCAGCGACCCCTCAAGGTGGATATTAAAACTGAAAGCAGTGCTTAACTCTTCCTGG AGTATCTACATGAAAAAAACAACATTCTGAAAATTTCACATTAAAAAAAAAGCTTCATAG AAGTCACTTTGAAATGCTAAAATAGCCAAAGGCCAGAAATTGAGGGTATAAAAACTCCAT T |
| Restriction Sites | NotI-NotI |
| ACCN | NM_012420 |
| Insert Size | 3410 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Reference Data | |
| RefSeq | NM_012420.1, NP_036552.1 |
| RefSeq Size | 3906 bp |
| RefSeq ORF | 1449 bp |
| Locus ID | 24138 |
| UniProt ID | Q13325 |
| Domains | TPR |
| Gene Summary | Interferon-induced RNA-binding protein involved in the human innate immune response. Has a broad and adaptable RNA structure recognition important for RNA recognition specificity in antiviral defense. Binds precursor and processed tRNAs as well as poly-U-tailed tRNA fragments (PubMed:25092312, PubMed:23317505, PubMed:23774268). Specifically binds single-stranded RNA bearing a 5'-triphosphate group (PPP-RNA), thereby acting as a sensor of viral single-stranded RNAs. Single-stranded PPP-RNAs, which lack 2'-O-methylation of the 5' cap and bear a 5'-triphosphate group instead, are specific from viruses, providing a molecular signature to distinguish between self and non-self mRNAs by the host during viral infection. Directly binds PPP-RNA in a non-sequence-specific manner (PubMed:23334420). Also recognizes and selectively binds AT-rich dsDNA (PubMed:23774268). Additionally, as a mediator in innate immunity, regulates positively IKK-NFKB signaling by sinergizing the recruitment of IKK to MAP3K7 (PubMed:26334375).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| RC206499 | IFIT5 (Myc-DDK-tagged)-Human interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) |
CNY 3,656.00 |
|
| RC206499L1 | Lenti ORF clone of Human interferon-induced protein with tetratricopeptide repeats 5 (IFIT5), Myc-DDK-tagged |
CNY 6,056.00 |
|
| RC206499L2 | Lenti ORF clone of Human interferon-induced protein with tetratricopeptide repeats 5 (IFIT5), mGFP tagged |
CNY 5,890.00 |
|
| RC206499L3 | Lenti ORF clone of Human interferon-induced protein with tetratricopeptide repeats 5 (IFIT5), Myc-DDK-tagged |
CNY 5,890.00 |
|
| RC206499L4 | Lenti ORF clone of Human interferon-induced protein with tetratricopeptide repeats 5 (IFIT5), mGFP tagged |
CNY 5,890.00 |
|
| RG206499 | IFIT5 (tGFP-tagged) - Human interferon-induced protein with tetratricopeptide repeats 5 (IFIT5) |
CNY 5,256.00 |
