Mesdc2 (BC014742) Mouse Tagged ORF Clone
CAT#: MG201440
- TrueORF®
Mesdc2 (tGFP-tagged) - Mouse mesoderm development candiate 2 (cDNA clone MGC:25959 IMAGE:4239248)
ORF Plasmid: DDK
"BC014742" in other vectors (4)
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CNY 2,850.00
CNY 1,000.00
Specifications
Product Data | |
Type | Mouse Tagged ORF Clone |
Tag | TurboGFP |
Synonyms | 2210015O11Rik; AW537813; mesd; mKIAA0081; msd |
Vector | pCMV6-AC-GFP |
E. coli Selection | Ampicillin (100 ug/mL) |
Mammalian Cell Selection | Neomycin |
Sequence Data |
>MG201440 representing BC014742
Red=Cloning site Blue=ORF Green=Tags(s) TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCGCGACTTCTGGAGCAGTGGGAGAAAGATGATGACATAGAAGAAGGAGACCTTCCAGAACACAAGA GACCCTCAGCACCTATCGACTTCTCAAAGCTAGACCCAGGCAAACCTGAGAGCATCTTGAAAATGACAAA GAAAGGGAAGACTCTGATGATGTTTGTCACCGTGTCTGGGAACCCCACCGAGAAGGAGACAGAGGAGATC ACCAGCCTGTGGCAGGGTAGCCTGTTCAACGCCAACTATGACGTTCAGAGGTTCATCGTGGGATCCGACC GCGCCATCTTCATGCTCCGGGATGGGAGCTATGCCTGGGAGATCAAGGACTTTTTGGTCAGTCAAGACCG GTGTGCTGAAGTCACTCTAGAGGGACAGATGTATCCTGGCAAAGGAGGAGGAAGCAAGGAGAAAAATAAA ACAAAGCCAGAGAAGGCTAAAAAGAAGGAGGGAGATCCCAAACCACGTGCTTCCAAGGAAGACAATCGAG CTGGGAGCAGAAGAGAAGACCTT ACGCGTACGCGGCCGCTCGAG - GFP Tag - GTTTAA >MG201440 representing BC014742
Red=Cloning site Green=Tags(s) MARLLEQWEKDDDIEEGDLPEHKRPSAPIDFSKLDPGKPESILKMTKKGKTLMMFVTVSGNPTEKETEEI TSLWQGSLFNANYDVQRFIVGSDRAIFMLRDGSYAWEIKDFLVSQDRCAEVTLEGQMYPGKGGGSKEKNK TKPEKAKKKEGDPKPRASKEDNRAGSRREDL TRTRPLE - GFP Tag - V |
Restriction Sites | SgfI-MluI Cloning Scheme for this gene Plasmid Map |
ACCN | BC014742 |
ORF Size | 515 bp |
OTI Disclaimer | The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info |
OTI Annotation | This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene. |
Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
Reference Data | |
RefSeq | BC014742, AAH14742 |
RefSeq Size | 1876 bp |
RefSeq ORF | 515 bp |
Locus ID | 67943 |
Gene Summary | Chaperone specifically assisting the folding of beta-propeller/EGF modules within the family of low-density lipoprotein receptors (LDLRs). Acts as a modulator of the Wnt pathway through chaperoning the coreceptors of the canonical Wnt pathway, LRP5 and LRP6, to the plasma membrane. Essential for specification of embryonic polarity and mesoderm induction (PubMed:12581525). Plays an essential role in neuromuscular junction (NMJ) formation by promoting cell-surface expression of LRP4 (PubMed:24140340). May regulate phagocytosis of apoptotic retinal pigment epithelium (RPE) cells (PubMed:27184668).[UniProtKB/Swiss-Prot Function] |
Documents
Product Manuals |
FAQs |
SDS |
Resources
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
MC206918 | Mesdc2 (untagged) - Mouse mesoderm development candiate 2 (cDNA clone MGC:25959 IMAGE:4239248), (10ug) |
CNY 3,230.00 |
|
MR201440 | Mesdc2 (Myc-DDK-tagged) - Mouse mesoderm development candiate 2 (cDNA clone MGC:25959 IMAGE:4239248) |
CNY 2,400.00 |
|
MR201440L3 | Lenti ORF clone of Mesdc2 (Myc-DDK-tagged) - Mouse mesoderm development candiate 2 (cDNA clone MGC:25959 IMAGE:4239248) |
CNY 4,750.00 |
|
MR201440L4 | Lenti ORF clone of Mesdc2 (mGFP-tagged) - Mouse mesoderm development candiate 2 (cDNA clone MGC:25959 IMAGE:4239248) |
CNY 4,750.00 |