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Daam2 (NM_001008231) Mouse Untagged Clone
CAT＃: MC223620
Daam2 (untagged) - Mouse dishevelled associated activator of morphogenesis 2 (Daam2), (10ug)
CNY 14,250.00
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 2310016D11Rik; AI843643; AW557870 |
| Vector | pCMV6-Entry |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>MC223620 representing NM_001008231
Red=Cloning site Blue=ORF Orange=Stop codon TTTTGTAATACGACTCACTATAGGGCGGCCGGGAATTCGTCGACTGGATCCGGTACCGAGGAGATCTGCC GCCGCGATCGCC ATGGCCCTCCGCAAGAGGAGTCCTCATGGCCTGGGCTTCCTTTGCTGCTTTGGAGGCAGTGACCTTCCCG AGATCGACCTCCGGGACAGCCACCCACTGCAGTATCTGGAGTTCTCCGGTCCCATCCCGAATCCTGAGGA GCTCAATGTCCGCTTTGCAGAGCTGGTGGATGAATTGGACCTCACAGATAAAAACCGAGAGGCTGTGTTT GCACTACCACCCGAGAAGAAATGGCAGATCTACTGCAGCAAGAGGAAGGAGCAGGAGGATCCCAACAAGC TGGCAACCAGTTGGCCTGAGTACTACATTGATCGTATCAATGCCATGGCCGCCATGCAGAATCTGTATGA AACTGAAGATGAGGAGACAGACAAGAGGAACCAAGTTGTAGAAGACCTGAAGACAGCCCTCCGGACACAA CCCATGAGGTTTGTGACCCGCTTCATCGATCTGGAAGGCCTGACCTGTCTGCTGAATTTCCTCCGGGGCA TGGACCACACCACCTGTGAAAGCCGCATCCACACATCTCTCATTGGCTGCATCAAGGCTCTGATGAACAA CTCTCAGGGCCGGGCACACGTCCTGGCACAACCTGAGGCCATCAGCATCATCGCTCAGAGCCTGCGCACA GAGAACAGCAAGACCAAAGTTGCAGTGCTGGAGATCCTGGGTGCAGTGTGCCTTGTACCCGGAGGCCACA AGAAGGTTCTACAGGCCATGCTACACTATCAGGCGTATGCAGCCGAGCGCACTCGTTTCCAGACTTTGCT GAATGAACTGGATCGAAGCTTAGGCCGCTACCGGGATGAGGTAAACCTGAAGACAGCCATCATGTCCTTC ATCAATGCTGTCCTCAATGCTGGCGCTGGAGAGGATAACCTGGAATTCCGCCTGCATCTCCGGTATGAGT TCCTGATGCTGGGGATCCAGCCAGTGATTGATAAACTCCGGCAACACGAGAATGCCATCCTGGACAAGCA TTTAGACTTCTTTGAGATGGTCCGGAATGAGGATGACCTGGAGCTAGCCAGGAGGTTTGACATGGTCCAC ATTGACACAAAAAGTGCCTCCCAGATGTTTGAGCTGATCCACAAGAAGCTGAAGCACACGGAAGCCTATC CCTGCCTGCTCTCTGTCCTGCACCACTGCCTGCAGATGCCCTACAAGCGGAATGGTGGCTACTTCCAGCA GTGGCAGCTCCTGGACCGAATCCTTCAACAGATTGTCCTCCAGGATGAGCGAGGGGTGGACCCTGACCTG GCCCCACTGGAAAACTTTAATGTCAAGAACATCGTTAACATGCTCATCAATGAGAATGAGGTGAAGCAGT GGAGGGACCAGGCAGAGAAGTTTCGGAAAGAACACATGGAACTCATGAGCCGGCTGGAGAGAAAAGAGCG GGAATGTGAGACAAAGACACTGGAGAAGGAGGAGATGATGCGGACGCTCAACAAGATGAAGGACAAACTG GCCCGCGAGTCCCAGGAGCTGCGCCAAGCTAGGGGACAAGTGGCAGAGCTGGTAGCCCGACATAATGAGA GCTCAACCGGCCCGGTGTCCTCCCCACCTCCCCCTGGAGGTCCACTCACCTTGTCTTCCTCCAGGACAAC CAATGATCTGCCTCCACCCCCACCACCTCTCCCCTTTGATAGCTGCCCACCCCCACCCGCACCACCCCTC CCTCCCGGAGGGCCTCCCATCCCCCCAGGTGCCCCACCCTGCTTCAGCTCAGGCCCACCCCCATCTCATG ACCCCTTCTCCAGCAATGAAGCCCCACTCAGGAAAAAGCGCATTCCCCAGCCTTCACACCCACTGAAGTC CTTCAACTGGGTCAAGCTGAATGAGGAGCGTGTTTCTGGCACCGTGTGGAATGAAATTGATGACTCGCAG GTATTTCGGATTCTGGACCTGGAAGACTTTGAAAAAATGTTCTCGGCATATCAGAGGCACCAGGCTTGCA TGCAGGAGGGGCCCCAGAGAGAGAGAGGAAATGTGAGAGACGGAGGGGCGGCGAGCAGACCTCTGCCAGC TGTGGAGGCGAGTGCCCACAGAACTGAGAAGGCTTCTAGGTCTATGGTATCAGCTACAGGTGCCAAGAAA GAACTGGGCTCCACGGAGGACATCTACATAACCTCCCGCAAGGTTAAAGAGCTGTCAGTCATCGATGGCC GGAGGGCCCAGAACTGTATCATTCTTCTCTCCAAGCTGAAGCTTTCTAATGATGAAATACGGCAGGCCAT CTTGCGGATGGATGAACAAGAAGACCTCGCTAAGGACATGCTGGAGCAGCTTCTCAAGTTCATCCCCGAG AAGAGCGACATTGATCTCCTAGAAGAGCACAAACATGAGATTGAGAGGATGGCGCGTGCAGATCGCTTCC TCTATGAAATGAGCAGGATCGACCATTACCAGCAACGGCTACAGGCCCTGTTCTTCAAGAAGAAGTTCCA GGAACGCCTGGCTGAGGCCAAGCCCAAAGTAGAAGCCATCCTGCTGGCCTCCCGGGAGCTGACTCTCAGC CAGCGCCTGAAGCAAATGCTGGAGGTGGTCCTAGCCATCGGCAACTTCATGAACAAGGGGCAGCGTGGCG GTGCCTATGGCTTCCGGGTAGCCAGTCTCAACAAGATCGCTGACACCAAGTCCAGCATTGACAGGAACAT CTCTCTGCTTCATTACCTGATCATGATCCTGGAGAAGCACTTCCCAGATATCCTGAACATGCCCTCAGAG CTAAAGCACCTATCAGAAGCTGCCAAAGTCAACCTGGCAGAGCTGGAGAAGGAGGTGAGCATTCTCAGGA GAGGCCTCCGAGCAGTGGAAGTGGAGTTGGAATATCAGAGACACCAGGCACGAGACCCCAATGACAAGTT CGTCCCTGTCATGAGTGACTTCATCACAGTGTCTAGCTTCAGCTTCTCAGAGCTGGAGGACCAGCTGAAT GAGGCCAGGGACAAGTTTGCCAAGGCACTGACACATTTCGGAGAGCAGGAGAGTAAGATGCAACCGGATG AATTCTTTGGCATCTTCGACACCTTCCTGCAGGCCTTCTTGGAGGCCCGGCAGGACCTGGAGGCCATGCG GAGGAGGAAGGAGGAAGATGAGCGGAGAGCACGTATGGAATTCATGTTGAAGGAACAGCGTGAGAAAGAG AGATGGCAGAGGCAGAGGAAGGTCTTGGCTGGCGGCGCCCTGGAGGAGAGCGGCGAGTTTGATGACCTAG TGTCAGCCCTGCGCTCTGGAGAAGTTTTCGATAAGGACTTAAGCAAGTTCAAGCGCAACCGGAAGCGGCC CGGGAGCCAGGTTCCGGAGGTCACCCGCGAGCGGGCCATAAACAGGCTAAATTATTGA ACGCGTACGCGGCCGCTCGAGCAGAAACTCATCTCAGAAGAGGATCTGGCAGCAAATGATATCCTGGATT ACAAGGATGACGACGATAAGGTTTAA |
| Restriction Sites | SgfI-MluI |
| ACCN | NM_001008231 |
| Insert Size | 3348 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | NM_001008231.2, NP_001008232.2 |
| RefSeq Size | 6045 bp |
| RefSeq ORF | 3348 bp |
| Locus ID | 76441 |
| UniProt ID | Q80U19 |
| Gene Summary | Key regulator of the Wnt signaling pathway, which is required for various processes during development, such as dorsal patterning, determination of left/right symmetry or myelination in the central nervous system (PubMed:22227309, PubMed:24091014, PubMed:25754822). Acts downstream of Wnt ligands and upstream of beta-catenin (CTNNB1) (PubMed:22227309, PubMed:25754822). Required for canonical Wnt signaling pathway during patterning in the dorsal spinal cord by promoting the aggregation of Disheveled (Dvl) complexes, thereby clustering and formation of Wnt receptor signalosomes and potentiating Wnt activity (PubMed:22227309). During dorsal patterning of the spinal cord, inhibits oligodendrocytes differentiation via interaction with PIP5K1A (PubMed:25754822). Also regulates non-canonical Wnt signaling pathway (PubMed:24091014). Acts downstream of PITX2 in the developing gut and is required for left/right asymmetry within dorsal mesentery: affects mesenchymal condensation by lengthening cadherin-based junctions through WNT5A and non-canonical Wnt signaling, inducing polarized condensation in the left dorsal mesentery necessary to initiate gut rotation (PubMed:24091014). Together with DAAM1, required for myocardial maturation and sarcomere assembly (PubMed:26526197).[UniProtKB/Swiss-Prot Function] |
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MG217480 | Daam2 (tGFP-tagged) - Mouse dishevelled associated activator of morphogenesis 2 (Daam2), (10ug) |
CNY 9,220.00 |
|
| MR217480 | Daam2 (Myc-DDK-tagged) - Mouse dishevelled associated activator of morphogenesis 2 (Daam2) |
CNY 7,768.00 |
|
| MR217480L3 | Lenti ORF clone of Daam2 (Myc-DDK-tagged) - Mouse dishevelled associated activator of morphogenesis 2 (Daam2) |
CNY 10,260.00 |
|
| MR217480L4 | Lenti ORF clone of Daam2 (mGFP-tagged) - Mouse dishevelled associated activator of morphogenesis 2 (Daam2) |
CNY 10,260.00 |
