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Cyfip1 (BC054429) Mouse Untagged Clone
CAT＃: MC206672
Cyfip1 (untagged) - Mouse cytoplasmic FMR1 interacting protein 1 (cDNA clone MGC:62612 IMAGE:5345535), (10ug)
CNY 8,728.00
货期*
现货
规格
Product images
经常一起买 (3)
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | P140SRA-1, Sra-1, mKIAA0068 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC054429
CGCAGACCAGGATGGCTGCCCAAGTGACACTAGAGGACGCACTGTCCAATGTGGACCTCCTGGAGGAGCT GCCTCTGCCTGACCAGCAGCCCTGCATCGAGCCCCCACCGTCCTCACTGCTCTATCAGCCAAATTTCAAC ACCAACTTTGAAGACAGAAATGCATTTGTCACTGGCATTGCAAGATACATCGAACAAGCAACTGTCCACT CTAGCATGAACGAGATGCTAGAGGAAGGCCAAGAGTATGCTGTCATGCTGTACACCTGGAGGAGCTGCTC CCGGGCCATCCCTCAGGTGAAGTGCAACGAGCAGCCGAATAGAGTTGAAATTTATGAGAAAACCGTGGAA GTCCTTGAACCCGAGGTCACAAAACTGATGAATTTTATGTACTTTCAGAGAAATGCCATCGAGCGGTTCT GTGGGGAAGTGAGACGCCTGTGTCACGCTGAGAGGAGAAAGGACTTTGTTTCTGAAGCCTACTTGATCAC CCTGGGCAAATTTATCAACATGTTTGCTGTGTTGGATGAGCTGAAGAACATGAAGTGCAGTGTGAAGAAT GACCACTCTGCATATAAGAGGGCTGCTCAGTTTTTACGTAAAATGGCAGATCCACAATCCATCCAGGAGT CACAGAATCTGTCCATGTTCCTGGCCAACCACAACAAGATTACACAATCTCTGCAGCAGCAGCTTGAGGT CATTTCTGGCTATGAAGAGCTCCTGGCAGACATCGTGAATCTGTGTGTGGATTACTATGAGAACAGGATG TACTTGACACCCAGCGAAAAACACATGCTTCTCAAAGTCATGGGATTTGGCCTGTACCTGATGGATGGGA GTGTGAGTAACATCTACAAACTAGATGCCAAGAAAAGAATAAATTTATCCAAAATCGACAAGTATTTCAA GCAGCTGCAGGTGGTTCCACTCTTTGGAGATATGCAAATAGAACTGGCAAGATACATCAAGACCAGCGCA CACTATGAGGAGAATAAGTCCCGGTGGACCTGCGCGTCCTCCAGCAGCAGCCCGCAGTACAACATCTGTG AGCAGATGATCCAGATCCGTGAGGACCATATGCGTTTCATCTCCGAGCTGGCACGCTACAGCAATAGCGA GGTAGTCACAGGGTCTGGCCGGCAGGAAGCCCAGAAGACAGATGCTGAGTACCGGAAGCTCTTCGATCTG GCTCTGCAGGGCCTGCAGCTTCTGTCGCAGTGGAGCGCTCACGTGATGGAAGTGTATTCCTGGAAACTTG TACATCCAACAGACAAGTACTCCAACAAGGACTGCCCCGACAACGCTGAGGAGTACGAGCGAGCCACACG CTACAACTACACCACTGAGGAGAAGTTTGCCCTGGTGGAGGTGATTGCCATGATCAAAGGCCTGCAGGTG CTGATGGGCAGGATGGAGAGTGTGTTCAATCACGCCATCAGACACACGGTTTACGCTGCGCTTCAGGACT TCTCCCAGGTGACCCTCAGGGAACCACTTCGACAGGCCATCAAGAAGAAAAAGAACGTAATCCAGAGTGT CCTACAGGCCATCAGGAAGACTGTGTGTGACTGGGAGACTGGGCATGAGCCCTTTAACGACCCAGCTCTG CGGGGAGAGAAGGACCCTAAGAGTGGCTTTGACATCAAGGTGCCACGCCGTGCTGTGGGACCCTCCAGCA CGCAGCTTTACATGGTGAGAACTATGCTAGAGTCCCTCATTGCAGACAAAAGTGGTTCCAAGAAAACCTT GAGAAGTAGCCTTGAGGGGCCCACCATATTGGACATAGAAAAATTTCATCGAGAATCATTCTTCTACACT CACTTGATAAATTTCAGTGAAACACTGCAGCAGTGCTGTGACCTTTCCCAGCTGTGGTTCCGAGAGTTCT TCCTGGAGCTGACCATGGGCAGGAGGATCCAGTTCCCCATTGAGATGTCTATGCCCTGGATTCTGACTGA TCACATCCTAGAGACCAAGGAGGCATCAATGATGGAGTACGTCCTCTACTCCTTGGACCTGTACAACGAC AGTGCCCACTATGCGCTCACCAAGTTCAACAAGCAGTTTCTCTATGATGAGATTGAGGCAGAGGTGAATC TGTGTTTTGACCAATTTGTTTATAAACTGGCAGACCAGATATTTGCATATTACAAGGTTATGGCAGGAAG TTTGCTTCTTGACAAAAGGTTACGGTCAGAATGCAAAAATCAGGGAGCCACGATCCACCTCCCCCCATCT AACCGCTATGAGACGCTGTTGAAGCAAAGGCACGTGCAGCTGCTCGGGAGATCCATTGATCTCAACCGTC TGATTACACAGCGCGTTTCAGCAGCCATGTACAAATCTCTAGAACTGGCAATTGGACGGTTTGAAAGTGA AGATTTAACATCAGTAGTCGAGCTAGATGGACTCTTAGAAATCAACCGTATGACACACAAGCTGTTGAGC AGGTACCTCACACTGGACAGCTTTGATGCCATGTTCCGGGAAGCCAACCACAACGTGTCTGCACCTTATG GAAGAATTACCCTCCACGTCTTCTGGGAGCTAAACTATGACTTCTTGCCCAACTACTGCTATAATGGCTC TACCAACCGGTTTGTTCGGACAGTATTACCATTTTCTCAGGAATTTCAAAGAGACAAACAGCCTAACGCA CAGCCCCAGTATTTGCATGGATCCAAGGCTTTGAACCTAGCCTACTCAAGCATTTATGGCAGCTACCGGA ACTTTGTGGGGCCTCCGCACTTCCAAGTCATCTGCCGGCTACTTGGCTACCAGGGCATTGCAGTAGTCAT GGAAGAGCTGCTGAAGGTTGTCAAGAGCCTGCTGCAAGGCACAATCCTACAGTACGTGAAAACTCTGATG GAAGTGATGCCCAAGATCTGCCGGCTTCCGCGACATGAGTACGGCTCTCCTGGCATCCTGGAGTTCTTCC ACCACCAGCTGAAGGACATTGTGGAGTATGCAGAGCTGAAAACCGTATGCTTCCAGAACCTGCGGGAGGT GGGCAATGCTGTTCTCTTCTGCCTGCTTATTGAGCAAAGCCTGTCTTTAGAAGAAGTCTGTGACCTGTTG CATGCAGCTCCTTTCCAGAATATCTTACCTCGAATCCATGTAAAAGAGGGGGAGAGAGTTGATGCCAAAA TGAAAAGACTAGAATCCAAGTATGCCCCACTGCACCTTGTCCCACTGATTGAAAGGCTGGGGACCCCACA GCAAATTGCAATTGCAAGAGAGGGGGACTTGCTGACCAAGGAGCGTCTCTGTTGTGGTCTGTCCATGTTT GAAGTCATCCTGACACGGATCCGGACCTTTCTGGATGATCCCATCTGGCGTGGGCCCCTACCCAGCAATG GTGTCATGCACGTGGATGAGTGTGTGGAGTTTCACAGACTATGGAGTGCCATGCAGTTTGTTTACTGCAT TCCTGTAGGGACACACGAGTTTACAGTGGAGCAGTGTTTTGGAGATGGGCTCCACTGGGCTGGCTGCATG ATCATTGTACTTCTTGGACAGCAGCGGCGCTTTGCTGTGTTGGATTTCTGCTATCATCTTCTCAAAGTTC AGAAACATGATGGCAAAGATGAGATCATCAAAAATGTGCCATTGAAGAAGATGGTGGAGAGGATCCGCAA GTTCCAGATTCTCAACGATGAAATCATCACTATCCTGGACAAGTACTTGAAATCTGGTGATGGCGAGAGC ACACCTGTGGAGCATGTACGCTGCTTCCAGCCACCCATCCACCAGTCCCTAGCCAGTAGCTGAGGGCTAA GCTCACAGCATCCCAGTAACTGATGGCATGTTTGTCTTTATGTAAACTATATTGAAATTTTTAGGGGCTA TTTTCCATTATGTCTGAACCTACTTTTGATCTGAAAGCTTAACTTTATAAAATTTACTTATTTTTCTATA CTAAAATTGTATATGCCTTTGGAATTGGGAAGTCTGAGAATACGGTTACTAGTTGTTGCCATTACGGTAT TAACAAGTATTTTCATGCCGAATATTCCAGCAGCTATTATAAAATGCTAAATTCACTCATCCTGTACGAG CATAATACCAACTAATTGTATTAAAAAAAAATAAAAAAACAAAAAAAAAAAAAAAA |
| Restriction Sites | EcoRI-NotI |
| ACCN | BC054429 |
| Insert Size | 3762 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC054429, AAH54429 |
| RefSeq Size | 4116 bp |
| RefSeq ORF | 3762 bp |
| Locus ID | 20430 |
| Gene Summary | Component of the CYFIP1-EIF4E-FMR1 complex which binds to the mRNA cap and mediates translational repression. In the CYFIP1-EIF4E-FMR1 complex this subunit is an adapter between EIF4E and FMR1. Promotes the translation repression activity of FMR1 in brain probably by mediating its association with EIF4E and mRNA (By similarity). Regulates formation of membrane ruffles and lamellipodia. Plays a role in axon outgrowth. Binds to F-actin but not to RNA. Part of the WAVE complex that regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1. Regulator of epithelial morphogenesis. May act as an invasion suppressor in cancers. As component of the WAVE1 complex, required for BDNF-NTRK2 endocytic trafficking and signaling from early endosomes (PubMed:27605705).[UniProtKB/Swiss-Prot Function] |
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