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Mbtps1 (NM_019709) Mouse Untagged Clone
CAT＃: MC204593
Mbtps1 (untagged) - Mouse membrane-bound transcription factor peptidase, site 1 (Mbtps1), transcript variant 1, (10ug)
CNY 7,336.00
| Cited in 1 publication. |
Product images
Specifications
| Product Data | |
| Type | Mouse Untagged Clone |
| Tag | Tag Free |
| Synonyms | 0610038M03Rik; AV003995; mKIAA0091; S1P; SKI-1; Ski1 |
| Vector | PCMV6-Kan/Neo |
| E. coli Selection | Kanamycin (25 ug/mL) |
| Mammalian Cell Selection | Neomycin |
| Sequence Data |
>BC057198
CCCGAATGGAGACCCGAGGCGTGTTCGCGGCGGAGCCGCCGTTCTCCCGGGTCCGCCGACCCCGAGCCTG AGGCGGACGCAGAATTCGGCCCCTGCCTAGTTTGTAAACATCAGCGATCTCTCCTGCACAGGGTACATCC TATAGAAACTGACTGTCTACCTGTGGAAGCGTTATCCAGGACAGTGCTAAAGTGACTCAGTGCAGGCAGG CCTCTCAAGATGCTCTCACAGGTCCGCTACAGAGCGGTGGATTGGGCATCCTGCTAGATTTGGGTCTGTG GCGCAAATGGAGTTTAGGACTCAGTGGACTCGGCCTCAATGAGAGAAGCCCCTGTCCAAGATGGAGAAGA AGCGGAGAAAGAAATGAAAGCCTCTCTTTGGGCCAAACCGTGGGTGACCATGGGACTGAGGTTTTCTTTA TGTTGGACAAGTCTGTAGGATGGCTGATCAGTAAGGCTGCAGCTTTTAGCCAGAACAGAAACCCACTTCT GATCAAGGAAGAGCCTCGTGCGATTTGAATTTATGCAATTTTCTGACCATATTCACTGAGGACCATGAAG CTCGTCAGCACCTGGCTTCTTGTGCTGGTGGTTTTGCTCTGTGGGAAACGGCACCTGGGCGACAGGCTGG GGACGAGAGCTTTGGAAAAGGCCCCGTGCCCCAGCTGCTCCCACCTGACTTTGAAGGTGGAATTCTCTTC AACTGTGGTGGAGTACGAATATATTGTGGCTTTCAACGGATACTTCACAGCCAAAGCTAGAAACTCATTT ATTTCAAGTGCTCTGAAAAGCAGTGAAGTGGAAAACTGGAGAATAATACCTCGGAACAACCCATCCAGTG ACTACCCTAGTGATTTTGAGGTGATTCAGATAAAAGAGAAGCAGAAGGCGGGGCTGCTCACACTTGAAGA TCACCCCAACATCAAGCGGGTGACACCCCAGCGGAAAGTCTTTCGTTCCCTCAAGTTTGCTGAATCCAAC CCCATCGTGCCCTGTAATGAAACCCGGTGGAGCCAGAAGTGGCAGTCATCACGTCCCCTGAAAAGAGCCA GTCTCTCCCTGGGCTCTGGATTCTGGCATGCAACAGGAAGACATTCAAGTCGGCGATTGCTGAGAGCCAT TCCTCGCCAGGTCGCCCAGACACTGCAGGCAGATGTGCTGTGGCAGATGGGATACACAGGTGCTAATGTC AGAGTTGCTGTTTTTGATACTGGGCTCAGTGAGAAGCATCCGCATTTTAAGAATGTGAAGGAGAGAACCA ACTGGACCAATGAGCGGACCCTGGATGATGGGCTAGGCCATGGCACATTCGTTGCAGGTGTGATTGCCAG CATGAGGGAGTGCCAAGGATTTGCTCCAGATGCAGAGCTGCACATCTTCAGGGTCTTTACCAACAATCAG GTGTCTTACACATCTTGGTTTCTGGATGCCTTCAACTATGCCATCCTAAAGAAGATGGACGTTCTCAACC TTAGCATCGGTGGGCCCGACTTCATGGATCATCCGTTTGTTGACAAGGTGTGGGAATTAACAGCTAACAA TGTAATTATGGTTTCTGCTATTGGCAATGATGGACCTCTCTATGGCACTCTGAATAACCCTGCTGATCAG ATGGATGTGATTGGAGTGGGTGGCATTGACTTTGAAGATAACATCGCTCGCTTTTCTTCCAGGGGAATGA CTACCTGGGAATTACCAGGAGGCTATGGTCGTGTGAAGCCTGACATTGTCACCTATGGTGCTGGAGTGCG GGGTTCCGGTGTGAAAGGGGGCTGCCGTGCACTCTCAGGGACCAGTGTCGCTTCCCCAGTGGTCGCTGGG GCCGTCACCTTGTTAGTAAGCACAGTACAGAAGCGGGAGCTGGTGAATCCTGCCAGTGTGAAGCAAGCTT TGATAGCGTCAGCCCGGAGACTTCCTGGGGTCAACATGTTCGAGCAAGGTCATGGCAAGTTGGATCTGCT GCGAGCTTATCAGATCCTCAGCAGCTATAAACCGCAGGCAAGCCTGAGTCCTAGCTACATCGACCTGACT GAGTGTCCCTACATGTGGCCCTACTGCTCCCAGCCTATCTACTATGGAGGAATGCCAACAATCGTTAATG TCACCATCCTCAATGGCATGGGCGTCACAGGAAGAATTGTGGATAAGCCTGAGTGGCGACCCTATTTACC ACAGAATGGAGACAACATTGAAGTGGCCTTCTCCTACTCCTCAGTGTTGTGGCCCTGGTCAGGTTACCTT GCCATCTCCATTTCTGTGACCAAGAAGGCAGCTTCCTGGGAAGGCATCGCTCAGGGCCACATCATGATCA CAGTGGCGTCCCCAGCAGAGACAGAGTTACACAGTGGTGCGGAGCACACTTCCACCGTGAAGCTGCCCAT CAAGGTGAAGATCATTCCCACCCCTCCTCGGAGCAAGAGAGTCCTCTGGGACCAGTACCACAACCTCCGC TACCCACCTGGCTACTTCCCCAGGGACAACTTGCGGATGAAGAATGACCCTTTAGACTGGAATGGCGACC ACGTCCACACCAACTTCAGGGACATGTACCAGCATCTGCGCAGCATGGGCTACTTCGTGGAGGTGCTCGG CGCCCCATTCACATGTTTTGACGCCACACAGTATGGCACTTTGCTGCTGGTGGACAGTGAGGAAGAGTAC TTCCCTGAGGAGATTGCTAAGCTGAGGAGGGATATGGACAATGGCCTTTCCCTCGTCATCTTCAGTGACT GGTACAACACTTCTGTTATGAGAAAAGTGAAGTTTTATGATGAAAACACCAGGCAGTGGTGGATGCCAGA CACCGGAGGAGCGAACATCCCAGCTCTGAATGAGCTGCTGTCTGTGTGGAACATGGGGTTCAGTGACGGC CTATATGAAGGGGAGTTTGTCCTGGCAAACCATGACATGTACTATGCGTCGGGGTGCAGCATCGCCAAGT TTCCAGAAGATGGCGTCGTGATCACACAGACTTTCAAGGACCAAGGATTGGAGGTCTTAAAACAAGAGAC AGCAGTTGTGGAAAATGTTCCCATTTTGGGGCTTTATCAGATTCCATCTGAAGGTGGAGGCCGGATCGTG CTGTATGGAGACTCCAACTGCTTGGATGACAGTCACAGACAGAAGGACTGCTTTTGGCTTCTGGATGCGC TCCTTCAGTACACATCCTATGGCGTGACCCCTCCCAGCCTCAGCCATTCAGGGAACCGGCAGCGCCCACC TAGCGGAGCCGGCTTGGCCCCTCCTGAAAGGATGGAAGGAAACCACCTCCATCGGTACTCCAAAGTTCTT GAAGCCCACTTGGGAGACCCGAAACCTCGGCCCCTGCCAGCCTGTCCACATTTGTCATGGGCCAAGCCAC AGCCTTTGAATGAGACGGCACCCAGTAATCTTTGGAAACATCAGAAGCTGCTCTCCATTGACCTGGACAA AGTAGTGTTACCCAACTTTCGATCCAATCGCCCTCAAGTGAGACCTTTGTCCCCTGGAGAGAGTGGTGCC TGGGACATTCCTGGAGGGATCATGCCTGGCCGCTACAACCAGGAGGTGGGACAGACCATCCCCGTCTTCG CCTTCCTCGGAGCCATGGTGGCCCTGGCCTTCTTTGTGGTACAGATCAGCAAGGCCAAGAGCCGGCCGAA GCGGAGGAGGCCCAGGGCAAAGCGTCCACAACTTGCACAGCAGGCCCACCCTGCAAGGACCCCATCAGTG TGAGCATCGCAGTAGCCAGCCACAGAAGCTAACAAGCCTTGAACCACTCTGGTGGCCACACAGCGCCTCA GAGAGCATTCTGGGAAGTGCCTGTTTCCGAGGAACCCTGTCTCCAGCTTGTGGCTATCTTACTGTGTTCT GCCCAGGCACCTGATGAGGTACATCCTGCAGTGCCTCTCTGTGCTTGGCTCTGGCAGAAGGCACCCAGTG ACATCAGGCATCAGGCCCAGTGACAGTGCACCAAAGACACAGAGCCTGGAAGGGCTGTCGGGACATACTT TCTACATAACGCTACAACCCTGACCAAGCAAAGACATGCTTGTTACAGGCTATTTTCTATATTTATTGTG GGAGAGTCACTTTAAAGACTGTGCTAGTTGGAAACAGAGCTGTTGCTGTTGTCAGTCGAGTGCAGTTTTC TGCAGCGATGTCATAAGGAGTCAGATTCCGTGACCTCCTCTTTGATGGAGGACACACTGAACTGAAGGGG ACTTGCGCGGATGTGGGAGATGCAAGCCTTCGCTTTATTTTTTTATAACTATCAACTGCCATCATGTTTT GTAATTTGGGGATCTTGATTTCACCGTTGTTGGTGAAGGAAATTTTCAATAAATATGCATAACCTTAAAA AAAAAAAAAAAAAAAAAAAA |
| Restriction Sites | RsrII-NotI |
| ACCN | NM_019709 |
| Insert Size | 3159 bp |
| OTI Disclaimer | Our molecular clone sequence data has been matched to the reference identifier above as a point of reference. Note that the complete sequence of our molecular clones may differ from the sequence published for this corresponding reference, e.g., by representing an alternative RNA splicing form or single nucleotide polymorphism (SNP). |
| Product Components | The ORF clone is ion-exchange column purified and shipped in a 2D barcoded Matrix tube containing 10ug of transfection-ready, dried plasmid DNA (reconstitute with 100 ul of water). |
| Reconstitution | 1. Centrifuge at 5,000xg for 5min. 2. Carefully open the tube and add 100ul of sterile water to dissolve the DNA. 3. Close the tube and incubate for 10 minutes at room temperature. 4. Briefly vortex the tube and then do a quick spin (less than 5000xg) to concentrate the liquid at the bottom. 5. Store the suspended plasmid at -20°C. The DNA is stable for at least one year from date of shipping when stored at -20°C. |
| Note | Plasmids are not sterile. For experiments where strict sterility is required, filtration with 0.22um filter is required. |
| Reference Data | |
| RefSeq | BC057198, AAH57198 |
| RefSeq Size | 4360 bp |
| RefSeq ORF | 3159 bp |
| Locus ID | 56453 |
| UniProt ID | Q9WTZ2 |
| Gene Summary | Serine protease that catalyzes the first step in the proteolytic activation of the sterol regulatory element-binding proteins (SREBPs). Other known substrates are BDNF, GNPTAB and ATF6. Cleaves after hydrophobic or small residues, provided that Arg or Lys is in position P4. Cleaves known substrates after Arg-Ser-Val-Leu (SERBP-2), Arg-His-Leu-Leu (ATF6), Arg-Gly-Leu-Thr (BDNF) and its own propeptide after Arg-Arg-Leu-Leu. Mediates the protein cleavage of GNPTAB into subunit alpha and beta, thereby participating in biogenesis of lysosomes (By similarity).[UniProtKB/Swiss-Prot Function] Transcript Variant: This variant (1) represents the longer transcript. Variants 1 and 2 encode the same protein. |
Citations (1)
| The use of this cDNA Clones has been cited in the following citations: |
|---|
|
ER Stress Drives Lipogenesis and Steatohepatitis via Caspase-2 Activation of S1P
,null,
Cell
,PubMed ID 30220454
[Mbtps1]
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Resources
Other Versions
| SKU | Description | Size | Price |
|---|---|---|---|
| MC223144 | Mbtps1 (untagged) - Mouse membrane-bound transcription factor peptidase, site 1 (Mbtps1), transcript variant 1, (10ug) |
CNY 12,920.00 |
|
| MG211541 | Mbtps1 (tGFP-tagged) - Mouse membrane-bound transcription factor peptidase, site 1 (Mbtps1) |
CNY 9,220.00 |
|
| MG220424 | Mbtps1 (tGFP-tagged) - Mouse membrane-bound transcription factor peptidase site 1 (Mbtps1) transcript variant 1, (10ug) |
CNY 9,220.00 |
|
| MR220424 | Mbtps1 (Myc-DDK-tagged) - Mouse membrane-bound transcription factor peptidase, site 1 (Mbtps1), transcript variant 1 |
CNY 7,328.00 |
|
| MR220424L3 | Lenti ORF clone of Mbtps1 (Myc-DDK-tagged) - Mouse membrane-bound transcription factor peptidase, site 1 (Mbtps1), transcript variant 1 |
CNY 10,260.00 |
|
| MR220424L4 | Lenti ORF clone of Mbtps1 (mGFP-tagged) - Mouse membrane-bound transcription factor peptidase, site 1 (Mbtps1), transcript variant 1 |
CNY 10,260.00 |
