Frizzled 6 (FZD6) (NM_003506) Human 3' UTR Clone

Specifications

Product Data
Product Name	Frizzled 6 (FZD6) (NM_003506) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	FZ-6; FZ6; HFZ6; NDNC1; NDNC10
ACCN	NM_003506
Insert Size	1387 bp
Sequence Data	Insert Sequence (showhide) >SC214183 3’UTR clone of NM_003506 The sequence shown below is from the reference sequence of NM_003506. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGGGAGGTGGTTGTCATTCAGATACTTGAAGAACATTTTCTCTCGTTACTCAGAAGCAAATTTGTGTT ACACTGGAAGTGACCTATGCACTGTTTTGTAAGAATCACTGTTACATTCTTCTTTTGCACTTAAAGTTG CATTGCCTACTGTTATACTGGAAAAAATAGAGTTCAAGAATAATATGACTCATTTCACACAAAGGTTAA TGACAACAATATACCTGAAAACAGAAAATGTGCAGGTTAATAATATTTTTTTAATAGTGTGGGAGGACA GAGTTAGAGGAATCTTCCTTTTCTATTTATGAAGATTCTACTCTTGGTAAGAGTATTTTAAGATGTACT ATGCTATTTTACTTTTTTGATATAAAATCAAGATATTTCTTTGCTGAAGTATTTAAATCTTATCCTTGT ATCTTTTTATACATATTTGAAAATAAGCTTATATGTATTTGAACTTTTTTGAAATCCTATTCAAGTATT TTTATCATGCTATTGTGATATTTTAGCACTTTGGTAGCTTTTACACTGAATTTCTAAGAAAATTGTAAA ATAGTCTTCTTTTATACTGTAAAAAAAGATATACCAAAAAGTCTTATAATAGGAATTTAACTTTAAAAA CCCACTTATTGATACCTTACCATCTAAAATGTGTGATTTTTATAGTCTCGTTTTAGGAATTTCACAGAT CTAAATTATGTAACTGAAATAAGGTGCTTACTCAAAGAGTGTCCACTATTGATTGTATTATGCTGCTCA CTGATCCTTCTGCATATTTAAAATAAAATGTCCTAAAGGGTTAGTAGACAAAATGTTAGTCTTTTGTAT ATTAGGCCAAGTGCAATTGACTTCCCTTTTTTAATGTTTCATGACCACCCATTGATTGTATTATAACCA CTTACAGTTGCTTATATTTTTTGTTTTAACTTTTGTTTTTTAACATTTAGAATATTACATTTTGTATTA TACAGTACCTTTCTCAGACATTTTGTAGAATTCATTTCGGCAGCTCACTAGGATTTTGCTGAACATTAA AAAGTGTGATAGCGATATTAGTGCCAATCAAATGGAAAAAAGGTAGTTTTAATAAACAAGACACAACGT TTTTATACAACATACTTTAAAATATTAAGGAGTTTTCTTAATTTTGTTTCCTATTAAGTATTATTCTTT GGGCAAGATTTTCTGATGCTTTTGATTTTCTCTCAATTTAGCATTTGCTTTTGGTTTTTTTCTCTATTT AGCATTCTGTTAAGGCACAAAAACTATGTACTGTATGGGAAATGTTGTAAATATTACCTTTTCCACATT TTAAACAGACAACTTTGAATACAAAAACTTTGTTTTGTGTGATCTTTTCATTAATAAAATTATCTTTGT ATAAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003506.4
Synonyms	FZ-6; FZ6; HFZ6; NDNC1; NDNC10
Summary	This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members, this protein does not contain a C-terminal PDZ domain-binding motif. This protein functions as a negative regulator of the canonical Wnt/beta-catenin signaling cascade, thereby inhibiting the processes that trigger oncogenic transformation, cell proliferation, and inhibition of apoptosis. Alternative splicing results in multiple transcript variants, some of which do not encode a protein with a predicted signal peptide.[provided by RefSeq, Aug 2011]
Locus ID	8323
MW	55.2

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