Prostaglandin E Synthase (PTGES) (NM_004878) Human 3' UTR Clone

Specifications

Product Data
Product Name	Prostaglandin E Synthase (PTGES) (NM_004878) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MGST-IV; MGST1-L1; MGST1L1; MPGES; mPGES-1; PGES; PIG12; PP102; PP1294; TP53I12
ACCN	NM_004878
Insert Size	1292 bp
Sequence Data	Insert Sequence (showhide) >SC213630 3’UTR clone of NM_004878 The sequence shown below is from the reference sequence of NM_004878. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATCCTCTGGGAAGCGGCCCGCCACCTGTGACCAGCAGCTGATGCCTCCTTGGCCACCAGACCATGGGCC AAGAGCCGCCGTGGCTATACCTGGGGACTTGATGTTCCTTCCAGATTGTGGTGGGCCCTGAGTCCTGGT TTCCTGGCAGCCTGCTGCGCGTGTGGGTCTCTGGGCACAGTGGGCCTGTGTGTGTGCCCGTGTGTGTGT ATGTGTGTGTGTATGTTTCTTAGCCCCTTGGATTCCTGCACGAAGTGGCTGATGGGAACCATTTCAAGA CAGATTGTGAAGATTGATAGAAAATCCTTCAGCTAAAGTAACAGAGCATCAAAAACATCACTCCCTCTC CCTCCCTAACAGTGAAAAGAGAGAAGGGAGACTCTATTTAAGATTCCCAAACCTAATGATCATCTGAAT CCCGGGCTAAGAATGCAGACTTTTCAGACTGACCCCAGAAATTCTGGCCCAGCCAATCTAGAGGCAAGC CTGGCCATCTGTATTTTTTTTTTTCCAAGACAGAGTCTTGCTCTGTTGCCCAAGCTGGAGTGAAGTGGT ACAATCTGGCTCACTGCAGCCTCCGCCTCCCGGGTTCAAGCGATTCTCCCGCCTCAGCCTCCTGAGTAG CTGGGATTACAGGCGCGTATCACCATACCCAGCTAATTTTTGTATTTTTAGTAGAGACGGGTTCACCAT GTTGCCCAGGAGGGTCTCGAACTCCTGGCCTCAAGTGATCCACCGGCCTCGGCCTCCCAAAGTGCTGGG ATGACAGGCATGAATCACTGTGCTCAGCCACCATCTGGAGTTTTAAAAGGCTCCCATGTGAGTCCCTGT GATGGCCAGGCCAGGGGACCCCTGCCAGTTCTCTGTGGAAGCAAGGCTGGGGTCTTGGGTTCCTGTATG GTGGAAGCTGGGTGAGCCAAGGACAGGGCTGGCTCCTCTGCCCCCGCTGACGCTTCCCTTGCCGTTGGC TTTGGATGTCTTTGCTGCAGTCTTCTCTCTGGCTCAGGTGTGGGTGGGAGGGGCCCACAGGAAGCTCAG CCTTCTCCTCCCAAGGTTTGAGTCCCTCCAAAGGGCAGTGGGTGGAGGACCGGGAGCTTTGGGTGACCA GCCACTCAAAGGAACTTTCTGGTCCCTTCAGTATCTTCAAGGTTTGGAAACTGCAAATGTCCCCTTGAT GGGGAATCCGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTGTTTTCTCCTAGAC CCGTGACCTGAGATGTGTGATTTTTAGTCATTAAATGGAAGTGTCTGCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004878.5
Synonyms	MGST-IV; MGST1-L1; MGST1L1; MPGES; mPGES-1; PGES; PIG12; PP102; PP1294; TP53I12
Summary	The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. [provided by RefSeq, Jul 2008]
Locus ID	9536
MW	45.6

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