DMTF1 (NM_001142326) Human 3' UTR Clone

Specifications

Product Data
Product Name	DMTF1 (NM_001142326) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	DMP1; DMTF; hDMP1; MRUL
ACCN	NM_001142326
Insert Size	1215 bp
Sequence Data	Insert Sequence (showhide) >SC213063 3’UTR clone of NM_001142326 The sequence shown below is from the reference sequence of NM_001142326. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GATGTCGAAGATTTGGTAAACTGTCATTAGAATAATTCTTAGAAATAGGCAGTTCAAGCAAAGAAGGCA CACTGTTAATTACAACCTCTTCAAAGAAATAGGAGCAACCCCCAAGAGGCTTAATTTACCAATTTAAAT AGCCACAGTCCTTAAGCCACACACATTGTTGCTGCTATGACTTTTTACCTCCTTTAAACACATCATCTG AGGTTGAGTTTTATGACAGTATGTAGTTGAGTGGAGGCTGGGAGTTTTAAGCATAAATCCCTGTTTAGT GTTACATGGGAATAAGGAATTTCATTCACTTCAGCCACTAAGAAAAGTTTAGAATCACGAAAGCTTAAC TGCTGTGGTTTAAAGTACAGTTTCTCTAAAGATCAGACATGGCACTGTCTCCTCTCAAGCCTGGTTGTA GTTCAGATGAGTCTTTTCAACATGGTCTTCAACATGGTCTAGAGCTTACCAGTGATCTTCTGATCTTCA AGAAGACTAAGTTTGAGACTTGACCAGCATACAAGTATAGAGACCTAGGAGGTGGTCTTGTGGTGGTAC ATTTGGTTAACCCATTGCTGGCAGTGGGAGCTGATTTAGGCAGGGTAAACAGGAAAGCATTAAAAGTTA AAATTCACTACAGGTTTTTTGTTACTTTTAAAGGGAATATGGATAAGCATAGTAACAAAACCCACCAGA ATCTAAGCAGTTTTCACCCCCTCAGAAACCACTGTCATTAGTTTACAAAGTTAGCACTTTGAAGTAAAA CTAAATGAGGAAGGAAGTAATGTTACCTATCCTTGATACCATGACCATTTATTAGATGTTTTGCTATAT AAATTACCGAGAGAATAGTTTGTCATCCACTTAGTGTGTTAGCTGGTGGGGTACAATATAACCTCTCAT CTCAGGCTATTTTAAAAAAACAATATTTGCTTCTATAACAAAAGGAAACAAATCTAAGAATCATTCCTG TACTACAGAAGGGTTAAGGCAAAGGTAGCCTTTTGGGCTTTTTAATGAATATGACCCCTATAGAAAAGT CAAGAAAAAAAAACCCTTGTATAAATTATTTTATTTATTATTGTAATTAGATCTTCACAAAGTTGTCTT TTCACTGTGTTTTGTCAACGTGAAATTAAATTGTAGTTATAAGCAAAAGTTGGTTGCCTAGGGAACAAT TGTATATTCAGTTTAACAGAAATAAAAGAATATTTGTCTTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001142326.2
Synonyms	DMP1; DMTF; hDMP1; MRUL
Summary	This gene encodes a transcription factor that contains a cyclin D-binding domain, three central Myb-like repeats, and two flanking acidic transactivation domains at the N- and C-termini. The encoded protein is induced by the oncogenic Ras signaling pathway and functions as a tumor suppressor by activating the transcription of ARF and thus the ARF-p53 pathway to arrest cell growth or induce apoptosis. It also activates the transcription of aminopeptidase N and may play a role in hematopoietic cell differentiation. The transcriptional activity of this protein is regulated by binding of D-cyclins. This gene is hemizygously deleted in approximately 40% of human non-small-cell lung cancer and is a potential prognostic and gene-therapy target for non-small-cell lung cancer. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2008]
Locus ID	9988
MW	46.8

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