DOCK2 (NM_004946) Human 3' UTR Clone

Specifications

Product Data
Product Name	DOCK2 (NM_004946) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	IMD40
ACCN	NM_004946
Insert Size	554 bp
Sequence Data	Insert Sequence (showhide) >SC207296 3’UTR clone of NM_004946 The sequence shown below is from the reference sequence of NM_004946. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATCCCAGACTCGCTGTCCACGGACCTGTGAGCTGCTGCTGACTAGGGCTGCATGGGAGAGCCAGGGAGG GGAGTTTCTGGAAGAGGAAAGCCATGCGTGGAACATCGAAGCCTCAGAGAGTGGGAGACTGTCCCCATC AGTTGTCCTTACTTAGAGGAGACAGAGAGGCCAATCAGGTCCCAGAGCTTGAATGCTAACAAGCCCAGC ATCCCCTGGGGCTGTGATCATGGTGGATGAGGAAGCCTCAACGTAGATTCCTGAACTCAAGGTACCAGC AAGAATGCCTTCTCCCAGTGTGCTCTCCCCAACATCCTAGGCACAGCTTTCATAACCCAGTTTCTTAGG TGTAAGAAACTGTTTTTATCTCATTTATTAAGTCTCAGAACTTAACAGAAAAGGAAGCCTTTTAAATAT TCTTTTTAATTTTATTTTAGATTAACAGTTTTGTACTTTACATTTTTTTATACAACCAACCAGTTTCTT TTCTAGCCAATCATCTCTGAAGAGTTGCTGTTTCTTACTGACAATAAAAAATGTTCTCTTGGTTCGAAT AA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004946.3
Synonyms	IMD40
Summary	The protein encoded by this gene belongs to the CDM protein family. It is specifically expressed in hematopoietic cells and is predominantly expressed in peripheral blood leukocytes. The protein is involved in remodeling of the actin cytoskeleton required for lymphocyte migration in response to chemokine signaling. It activates members of the Rho family of GTPases, for example RAC1 and RAC2, by acting as a guanine nucleotide exchange factor (GEF) to exchange bound GDP for free GTP. Mutations in this gene result in immunodeficiency 40 (IMD40), a combined form of immunodeficiency that affects T cell number and function, also with variable defects in B cell and NK cell function. [provided by RefSeq, May 2018]
Locus ID	1794
MW	20.7

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