LIMS1 (NM_004987) Human 3' UTR Clone

Specifications

Product Data
Product Name	LIMS1 (NM_004987) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PINCH; PINCH-1; PINCH1
ACCN	NM_004987
Insert Size	442 bp
Sequence Data	Insert Sequence (showhide) >SC206234 3' UTR clone of NM_004987 The sequence shown below is from the reference sequence of NM_004987. The complete sequence of this clone may contain minor differences, such as SNPs. Red=Cloning site Blue=Stop Codon CAATTGGCAGAGCTCAGAATTCAAGCGATCGC CTAGCTGAGACCTTAGGAAGGAAATAAGTTCCTTTATTTTTTCTTTTCTATGCAAGATAAGAGATTACCA ACATTACTTGTCTTGATCTACCCATATTTAAAGCTATATCTCAAAGCAGTTGAGAGAAGAGGACCTATAT GAATGGTTTTATGTCATTTTTTTAATTAAAAAAGAAAAATTCATATAATCGTGTTTAAAACACAAATGAA GTCAGTATTTGCCTTTGTTAACCCTTATCCATTTGTTGACATGTAGACTGTTTACAAAAAAAAAACACAT GGTTAAATGTTAAATTTTAATTAAGGCCCCCAAAAATTAAATATAACTTTTTAAAATGAAAGGAGTCACC TTTTACATGACTCAGGTGAAAAAACAGTATAAACATTAATTTACTTTGTGTTCAAAAGAAAATTCCAACT GCTGTTGGGGAAGGACACAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004987.3
Synonyms	PINCH; PINCH-1; PINCH1
Summary	The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2010]
Locus ID	3987

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