VRK1 (NM_003384) Human 3' UTR Clone

Specifications

Product Data
Product Name	VRK1 (NM_003384) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PCH1; PCH1A
ACCN	NM_003384
Insert Size	431 bp
Sequence Data	Insert Sequence (showhide) >SC205713 3’UTR clone of NM_003384 The sequence shown below is from the reference sequence of NM_003384. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCAAGAACCAGAAAGAGAGTCCAGAAGTAATTCAGATGCTGTGAACCAGATTTCCTTTTCTTTGTTTTC TTTTGACTTTTTTCTCCTTTTCTATTTGAACTGTTTTATTTTCCTGTGAGTCTTGCGAGGTGGAAGTAA TGATTAAATACTCATGTGTTCAGAAAACATAAACTTTTTTTATAAAAATATTTTGTACAATTCATTAAA GGCTAATTTATGAAATTTGAAAATCTTCAGGTTATACTCCTTAAGTTATCCCAAAGCCGTGTGTTTGTG ATGTTTTGGAGTACATATATATGAAAATTATTATGACACGCACTTTTCTAATCATTGTACATTTCTCAG AGTGGATAAAAATGTTTGACAAAGTCCTCACTTTTAAGGAAATGCAAAGCTTAAAATAAAACTCTCTTT TGTTTGATGCAAACACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003384.3
Synonyms	PCH1; PCH1A
Summary	This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. This gene is widely expressed in human tissues and has increased expression in actively dividing cells, such as those in testis, thymus, fetal liver, and carcinomas. Its protein localizes to the nucleus and has been shown to promote the stability and nuclear accumulation of a transcriptionally active p53 molecule and, in vitro, to phosphorylate Thr18 of p53 and reduce p53 ubiquitination. This gene, therefore, may regulate cell proliferation. This protein also phosphorylates histone, casein, and the transcription factors ATF2 (activating transcription factor 2) and c-JUN. [provided by RefSeq, Jul 2008]
Locus ID	7443
MW	17.4

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