CLK2 (NM_003993) Human 3' UTR Clone

Specifications

Product Data
Product Name	CLK2 (NM_003993) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_003993
Insert Size	380 bp
Sequence Data	Insert Sequence (showhide) >SC205234 3’UTR clone of NM_003993 The sequence shown below is from the reference sequence of NM_003993. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TGGGACTCCAGTCGGGATATCAGTCGGTGACGATCAGGCCCTGGGCCCCCCTGCATCTTTTATAGCAGT GGGTGTCCAGTCCAGGACACTGGTGCTTTTTTATACAAGAGAACGAGCCAGAGTTCACTCCTTCCTCCT GGCTCTCTATATACCTGTGAATATGTGAAATAGTGTAAATATGAAAGAACTTGTACCTATCACTTCAAC CCCTGCCTTGTACATAATACTATTCCATCCACACAGTTTCCACCCTCACCTGCCCCCTCATACGGAGTT GGATGGGGGCCGAGTGAGGTAACCAGGTGGCATCTACCCCATGTTTTATAAGGAATTTTGTACAGTCTT TGTGAAATAAAATAACGTGCTTCATTTGACCCCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003993.4
Summary	This gene encodes a dual specificity protein kinase that phosphorylates serine/threonine and tyrosine-containing substrates. Activity of this protein regulates serine- and arginine-rich (SR) proteins of the spliceosomal complex, thereby influencing alternative transcript splicing. Chromosomal translocations have been characterized between this locus and the PAFAH1B3 (platelet-activating factor acetylhydrolase 1b, catalytic subunit 3 (29kDa)) gene on chromosome 19, resulting in the production of a fusion protein. Note that this gene is distinct from the TELO2 gene (GeneID:9894), which shares the CLK2 alias, but encodes a protein that is involved in telomere length regulation. There is a pseudogene for this gene on chromosome 7. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jun 2014]
Locus ID	1196
MW	14.1

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