Cip4 (TRIP10) (NM_004240) Human 3' UTR Clone

Specifications

Product Data
Product Name	Cip4 (TRIP10) (NM_004240) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CIP4; HSTP; STOT; STP; TRIP-10
ACCN	NM_004240
Insert Size	349 bp
Sequence Data	Insert Sequence (showhide) >SC204304 3’UTR clone of NM_004240 The sequence shown below is from the reference sequence of NM_004240. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACCTCCTACCTCCGAGTCACGCTCAATTGAACCCTGCCAGAGACGGGAAGAGGGGGGCTGTCGGCTGCT GCTTCTGGGCCACGGGGAGCCCCAGGACCTATGCACTTTATTTCTGACCCCGTGGCTTCGGCTGAGACC TGTGTAACCTGCTGCCCCCTCCACCCCCAACCCAGTCCTACCTGTCACACCGGACGGACCCGCTGTGCC TTCTACCATCGTTCCACCATTGATGTACATACTCATGTTTTACATCTTTTCTTTCTGCCGCTCGGCTCC GGCCATTTTGTTTTATACAAAAATGGGAAAAAAAAAAAAGAAATTATATAAAGTTCCTAGAGTCGGTGT CTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004240.4
Synonyms	CIP4; HSTP; STOT; STP; TRIP-10
Summary	Required for translocation of GLUT4 to the plasma membrane in response to insulin signaling (By similarity). Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. Binds to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promotes membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by recruiting WASL/N-WASP which in turn activates the Arp2/3 complex. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Required for the formation of podosomes, actin-rich adhesion structures specific to monocyte-derived cells. May be required for the lysosomal retention of FASLG/FASL.[UniProtKB/Swiss-Prot Function]
Locus ID	9322
MW	12.6

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