Prostaglandin D Synthase (PTGDS) (NM_000954) Human 3' UTR Clone

Specifications

Product Data
Product Name	Prostaglandin D Synthase (PTGDS) (NM_000954) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2
ACCN	NM_000954
Insert Size	194 bp
Sequence Data	Insert Sequence (showhide) >SC202050 3’UTR clone of NM_000954 The sequence shown below is from the reference sequence of NM_000954. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAAACCGATAAGTGCATGACGGAACAATAGGACTCCCCAGGGCTGAAGCTGGGATCCCGGCCAGCCAGG TGACCCCCACGCTCTGGATGTCTCTGCTCTGTTCCTTCCCCGAGCCCCTGCCCCGGCTCCCCGCCAAAG CAACCCTGCCCACTCAGGCTTCATCCTGCACAATAAACTCCGGAAGCAAGTCAGTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000954.6
Synonyms	L-PGDS; LPGDS; PDS; PGD2; PGDS; PGDS2
Summary	The protein encoded by this gene is a glutathione-independent prostaglandin D synthase that catalyzes the conversion of prostaglandin H2 (PGH2) to postaglandin D2 (PGD2). PGD2 functions as a neuromodulator as well as a trophic factor in the central nervous system. PGD2 is also involved in smooth muscle contraction/relaxation and is a potent inhibitor of platelet aggregation. This gene is preferentially expressed in brain. Studies with transgenic mice overexpressing this gene suggest that this gene may be also involved in the regulation of non-rapid eye movement sleep. [provided by RefSeq, Jul 2008]
Locus ID	5730
MW	6.8

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