CDT2 (DTL) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	FC, IF, IHC, WB
Recommend Dilution	WB: 1/1000-1/5000 IHC: 1/50-1/100 ICC/IF: 1/50-1/100 FC: 1/80
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	A synthesized peptide derived from human CDT2
Formulation	Rabbit IgG in phosphate buffered saline , pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Concentration	lot specific
Purification	Affinity Chromatography
Conjugation	Unconjugated
Storage Condition	Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.
Predicted Protein Size	91kDa
Gene Name	denticleless E3 ubiquitin protein ligase homolog
Database Link	Entrez Gene 51514 Human UniProt ID Q9NZJ0
Background	Swiss-Prot Acc.Q9NZJ0.Substrate-specific adapter of a DCX (DDB1-CUL4-X-box) E3 ubiquitin-protein ligase complex required for cell cycle control, DNA damage response and translesion DNA synthesis. The DCX(DTL) complex, also named CRL4(CDT2) complex, mediates the polyubiquitination and subsequent degradation of CDT1 and CDKN1A/p21(CIP1).
Synonyms	CDT2; CDW1; DCAF2; L2DTL; RAMP
Reference Data

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