SYT12 Rabbit Polyclonal Antibody

Specifications

Product Data
Reactivity	Human
Host	Rabbit
Clonality	Polyclonal
Immunogen	The immunogen is a synthetic peptide directed towards the N terminal region of human SYT12
Specificity	Expected reactivity: Cow, Horse, Human, Pig, Rabbit Homology: Cow: 79%; Horse: 79%; Human: 100%; Pig: 79%; Rabbit: 79%
Formulation	Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Concentration	lot specific
Purification	Affinity purified
Conjugation	Unconjugated
Storage Condition	For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
Predicted Protein Size	46 kDa
Gene Name	synaptotagmin 12
Database Link	NP_001171351.1 Entrez Gene 91683 Human UniProt ID Q8IV01
Background	This gene is a member of the synaptotagmin gene family and encodes a protein similar to other family members that mediate calcium-dependent regulation of membrane trafficking in synaptic transmission. Studies of the orthologous gene in rat have shown that the encoded protein selectively modulates spontaneous synaptic-vesicle exocytosis and may also be involved in regulating calcium independent secretion in nonneuronal cells. Alternative splicing results in multiple transcript variants. The gene has previously been referred to as synaptotagmin XI but has been renamed synaptotagmin XII to be standard with mouse and rat official nomenclature.
Synonyms	SRG1; SYT11; SytXII
Reference Data
Protein Families	Secreted Protein, Transmembrane

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