Plexin D1 (PLXND1) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IHC, WB
Recommend Dilution	WB: 200-1000 WB positive control: Hbmec cells IHC: 25-100 Positive control: Human prostate cancer Predicted cell location: Cytoplasm
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide of human PLXND1
Formulation	pH7.4 PBS, 0.05% NaN3, 40% Glyceroln
Concentration	lot specific
Purification	Antigen affinity purification
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Predicted Protein Size	212 kDa
Gene Name	plexin D1
Database Link	NP_055918 Entrez Gene 67784 MouseEntrez Gene 23129 Human UniProt ID Q9Y4D7
Background	Cell surface receptor for SEMA4A and for class 3 semaphorins, such as SEMA3A, SEMA3C and SEMA3E. Plays an important role in cell-cell signaling, and in regulating the migration of a wide spectrum of cell types. Regulates the migration of thymocytes in the medulla. Regulates endothelial cell migration. Plays an important role in ensuring the specificity of synapse formation. Required for normal development of the heart and vasculature By similarity. Mediates anti-angiogenic signaling in response to SEMA3E.
Synonyms	PLEXD1
Reference Data
Protein Families	Druggable Genome, Transmembrane

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