Acetylated Lysine Mouse Monoclonal Antibody [Clone ID: 15G10] Mouse Monoclonal Antibody [Clone ID: 15G10]

Specifications

Product Data
Clone Name	15G10
Applications	IF, WB
Recommend Dilution	WB, IF
Reactivity	Human
Host	Mouse
Clonality	Monoclonal
Immunogen	Acetylated protein mixture
Formulation	This antibody is provided in phosphate-buffered solution, pH 7.2, containing 0.09% sodium azide.
Concentration	lot specific
Purification	The antibody was purified by affinity chromatography.
Conjugation	Unconjugated
Storage Condition	Store at -20°C as received.
Background	Proteins are reversibly and dynamically acetylated on the ε-amino group of lysine by acetyltransferases and deacetylated by deacetylases. This post-translational modification can regulate protein function (interactions with other proteins and DNA binding). Histones and transcription factors (PCAF, p53, p300, etc) appear to be the major targets of acetytransferases. Acetylation is usually associated with chromatin remodeling and transcriptional activation, although in some cases (telomeres) it is associated with gene silencing. The 15G10 antibody recognizes acetylated lysine residues on proteins.
Reference Data

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