SSRP1 (C-term) Rabbit Polyclonal Antibody
CAT#: AP54054PU-N
SSRP1 (C-term) rabbit polyclonal antibody, Aff - Purified
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CNY 6,160.00
货期*
5周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | ELISA: 1/1000. Western Blot: 1/100-1/500. |
Reactivity | Human |
Host | Rabbit |
Clonality | Polyclonal |
Immunogen | KLH conjugated synthetic peptide between 489-518 amino acids from the C-terminal region of Human SSRP1. |
Specificity | This antibody recognizes Human SSRP1 / FACT80 (C-term). |
Formulation | PBS State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.09% Sodium Azide |
Concentration | lot specific |
Purification | Affinity Chromatography on Protein A |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. |
Gene Name | structure specific recognition protein 1 |
Database Link | |
Background | The protein encoded by this gene is a subunit of a heterodimer that, along with SUPT16H, forms chromatin transcriptional elongation factor FACT. FACT interacts specifically with histones H2A/H2B to effect nucleosome disassembly and transcription elongation. FACT and cisplatin-damaged DNA may be crucial to the anticancer mechanism of cisplatin. This encoded protein contains a high mobility group box which most likely constitutes the structure recognition element for cisplatin-modified DNA. This protein also functions as a co-activator of the transcriptional activator p63. An alternatively spliced transcript variant of this gene has been described, but its full-length nature is not known. |
Synonyms | FACT complex subunit SSRP1, FACTp80, T160 |
Note | Molecular Weight: 81075 Da |
Reference Data | |
Protein Families | Transcription Factors |
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