TXNDC5 (269-282) Goat Polyclonal Antibody

Specifications

Product Data
Applications	ELISA, IHC, WB
Recommend Dilution	Peptide ELISA: 1/64000 (Detection Limit). Western blot: 0.03-0.1 µg/ml. Approx 50+38kDa bands observed in Human Lymph Nodes lysates (calculated MW of 47.6kDa according to NP_110437.2 and of 36.2kDa according to NP_001139021.1). A 48kDa band was observed in Mouse Lymph Node while a 37-38kDa doublet was observed n Mouse Stomach lysates and in Mouse Intestine lysates. Immunohistochemistry on Paraffin Sections: 3.75 µg/ml (Human Small Intestine).
Reactivity	Bovine, Human, Mouse
Host	Goat
Clonality	Polyclonal
Immunogen	Peptide with sequence from the internal region of the protein sequence according to NP_110437.2; NP_001139021.1.
Specificity	Recognizes TXNDC5 (269-282). This antibody is expected to recognize both reported isoforms (NP_110437.2, NP_001139021.1) of TXNDC5.
Formulation	Tris saline, pH~7.3 State: Aff - Purified State: Liquid purified Ig fraction Stabilizer: 0.5% BSA Preservative: 0.02% Sodium Azide
Concentration	lot specific
Purification	Ammonium Sulphate Precipitation followed by antigen Affinity Chromatography using the immunizing peptide.
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Gene Name	thioredoxin domain containing 5
Database Link	Entrez Gene 105245 MouseEntrez Gene 81567 Human UniProt ID Q8NBS9
Background	ERp19 and ERp46 are two newly discovered ER luminal proteins, related to protein disulphide isomerase. Western and Northern blot analyses have revealed that both ERp19 and ERp46 and their respective mRNAs are highly expressed in the liver as compared with other tissues. Both proteins are enriched in purified liver ER vesicles and were localized specifically to the ER in McA-RH7777 hepatocytes. See Knoblach et al. for details.
Synonyms	ERp46
Reference Data
Protein Families	Druggable Genome

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