Neuroglycan C (CSPG5) Rabbit Polyclonal Antibody
CAT#: AP21148PU-S
Neuroglycan C (CSPG5) rabbit polyclonal antibody, Aff - Purified
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CNY 800.00
货期*
2周
规格
Specifications
Product Data | |
Applications | WB |
Recommend Dilution | Western blot: 1/500 - 1/1000. |
Reactivity | Human, Mouse, Rat |
Host | Rabbit |
Clonality | Polyclonal |
Specificity | This antibody detects endogenous levels of Neuroglycan C protein. (region surrounding Trp248) |
Formulation | Phosphate buffered saline (PBS), pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction Preservative: 15 mM sodium azide |
Concentration | 1.0 mg/ml |
Purification | Affinity chromatography (> 95% (by SDS-PAGE) |
Conjugation | Unconjugated |
Storage Condition | Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Predicted Protein Size | ~ 60 kDa |
Gene Name | chondroitin sulfate proteoglycan 5 |
Database Link | |
Background | Neuroglycan C is a transmembrane chondroitin sulfate proteoglycan that is exclusively expressed in the central nervous system. NGC gene expression is developmentally regulated being altered by addiction to psychostimulants and by nerve lesion. Its core protein has a particular multidomain structure differing from those of other known proteoglycans, and this protein is modified post-translationally in various ways such as phosphorylation and glycosylation. Neuroglycan C is a novel part-time proteoglycan that changes its structure from a proteoglycan form to a non-proteoglycan form without chondroitin sulfate chains during the development of the cerebellum and retina. Evidence suggests that Neuroglycan C is involved in neuronal circuit formation in the central nervous system. |
Synonyms | Chondroitin sulfate proteoglycan 5,CSPG5, CALEB, NGC |
Reference Data | |
Protein Families | ES Cell Differentiation/IPS, Transmembrane |
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