alpha 2C Adrenergic Receptor (ADRA2C) Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IF, IHC, WB
Recommend Dilution	Western blot: 1/500-1/1000. Immunohistochemistry on paraffin sections: 1/50-1/200. Immunofluorescence: 1/50-1/200.
Reactivity	Human, Mouse, Rat
Host	Rabbit
Clonality	Polyclonal
Immunogen	Synthetic peptide, corresponding to amino acids 340-390 of Human AR-α2C.
Specificity	This antibody detects endogenous levels of AR alpha2C protein. (region surrounding Arg369)
Formulation	Phosphate buffered saline (PBS), pH 7.2. State: Aff - Purified State: Liquid purified Ig fraction Preservative: 0.05% sodium azide
Concentration	1.0 mg/ml
Purification	Affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE)
Conjugation	Unconjugated
Storage Condition	Store undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing.
Predicted Protein Size	~ 70 kDa
Gene Name	adrenoceptor alpha 2C
Database Link	Entrez Gene 152 Human UniProt ID P18825
Background	Alpha-2C adrenergic receptors (alpha2C-AR) regulate neurotransmitter release from sympathetic nerves in the heart, and from adrenergic neurons in the central nervous system. alpha2C-AR can influence Parkinson’s disease, panic disorders, and Huntington disease (HD) progression. alpha2C-AR transcripts are present in rat muscle, heart, pancreas, and kidney.
Synonyms	ADRA2L2, ADRA2RL2, Alpha-2C adrenoreceptor, Alpha-2C adrenoceptor
Reference Data

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