SUPT16H Rabbit Polyclonal Antibody

Specifications

Product Data
Applications	IP, WB
Recommend Dilution	Western Blot: 5 - 10 µg/ml. Immunoprecipitation.
Reactivity	Human, Mouse
Host	Rabbit
Clonality	Polyclonal
Immunogen	Recombinant protein consisting of amino acids 321-640 of the human SPT16 protein conjugated to GST.
Specificity	This antibody reacts to FACT complex subunit SPT16.
Formulation	Phosphate buffered saline with 0.08% sodium azide State: Purified State: Liquid purified Ig
Concentration	lot specific
Conjugation	Unconjugated
Storage Condition	The antibody can be shipped at ambient temperature. Store (in aliquots) at -20°C only. Avoid repeated freezing and thawing.
Gene Name	SPT16 homolog, facilitates chromatin remodeling subunit
Database Link	Entrez Gene 11198 Human UniProt ID Q9Y5B9
Background	SPT16 and SSRP1 are found in all eurkaryotic cells and exists as part of an essential heterodimer complex. Together, SPT16 and SSRP1 are a highly abundant nuclear complex that in mammals has been called FACT, or Facilitates Chromatin Transcription. FACT enhances the processivity of RNA polymerase II through nucleosomes. Evidence also points to a role for FACT in replication, possibly by enhancing DNA polymerase through nucleosomes as well.
Synonyms	FACT complex subunit SPT16, FACTp140
Reference Data

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