LOC105369261 Mouse Monoclonal Antibody [Clone ID: DF-T1]
CAT#: AM08160SU-N
LOC105369261 mouse monoclonal antibody, clone DF-T1, Supernatant
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CNY 6,479.00
货期*
4周
规格
Specifications
Product Data | |
Clone Name | DF-T1 |
Applications | IHC |
Recommend Dilution | Immunohistochemistry on Formalin-Fixed, Paraffin-Embedded Sections: 1/100 Pretreatment of deperaffinized tissue with heat-induced epitope retrieval is recommended. Use Polymer anti Mouse/Rabbit IgG as a detection system. Positive Control: Tonsil, CLL/SLL, or lymph node. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Stimulated Human leukocytes. |
Specificity | Recognizes CD43. Cellular Localization: Cell membrane. |
Formulation | State: Supernatant State: Tissue Culture Supernatant with 0.2% BSA and 15mM Sodium Azide. |
Conjugation | Unconjugated |
Storage Condition | Store the antibody undiluted at 2-8°C. |
Database Link | |
Background | CD43 is a cell surface glycoprotein which is expressed on all thymocytes and T-cells. CD43 is involved in activation of T cells, B cells, NK cells, and monocytes. CD43, which is also known as leukosialin, galactoglycoprotein and sialophorin. CD43 is a sialomucin which like many mucins can have both adhesive and anti-adhesive functions. Expression of CD43 is found on most leukocytes except resting B lymphocytes. Proteolytic processing upon activation decreases surface expression. CD43 is involved in activation of T cells, B cells, NK cells, and monocytes. The counter-receptor for CD43 is CD169/SIGLEC-1, which is expressed on macrophages. |
Synonyms | Leukocyte sialoglycoprotein, Sialophorin, Galactoglycoprotein, SPN |
Reference Data | |
Protein Families | Druggable Genome, Secreted Protein, Transmembrane |
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