CD8A Mouse Monoclonal Antibody [Clone ID: 4B11]
CAT#: AM05530SU-T
CD8A mouse monoclonal antibody, clone 4B11
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CNY 3,310.00
货期*
4周
规格
Specifications
Product Data | |
Clone Name | 4B11 |
Applications | IHC |
Recommend Dilution | Immunohistochemistry on Frozen Sections: 1/20-1/40. Immunohistochemistry on paraffin sections: 1/20-1/40. This product requires antigen retrieval using heat treatment prior to staining of paraffin sections. 1mM EDTA pH 8.0 is recommended for this purpose. Positive Control Tissue: Human Tonsil. |
Reactivity | Human |
Host | Mouse |
Clonality | Monoclonal |
Immunogen | Synthetic peptide derived from CD8 alpha chain sequence. |
Specificity | This antibody recognizes the Human CD8 cell surface antigen, a 32kD glycoprotein expressed by the cytotoxic/suppressor subset of T-cells and weakly by NK cells. Clone 4B11 has been reported as being suitable for use in Western blotting. AM05530SU-N is recommended for this purpose. |
Formulation | State: Lyophilized Tissue Culture Supernatant containing 0.09% Sodium Azide as preservative. |
Reconstitution Method | Restore with 1 ml distilled water. |
Conjugation | Unconjugated |
Storage Condition | Prior to reconstitution store at 2-8°C. Following reconstitution store the antibody undiluted at 2-8°C for one month or (in aliquots) at -20°C for longer. Avoid repeated freezing and thawing. |
Gene Name | CD8a molecule |
Database Link | |
Background | The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell to cell interactions within the immune system. The CD8 antigen, acting as a coreceptor, and the T cell receptor on the T lymphocyte recognize antigen displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. |
Synonyms | CD8 alpha chain, CD8A, MAL |
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