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OriGene proteins in recent publications

Fully functional proteins purified from transient TrueORF cDNA clone transfections.  Researchers purified GEN1 protein using anti-FLAG M2 affinity column and determined it resolved Holliday junction X0 efficiently in vitro, thus confirming GEN1 is human Holliday junction resolvase.

Identification of Holliday junction resolvases from humans and yeast, Stephen C. Y. Ip, Ulrich Rass, Miguel G. Blanco, Helen R. Flynn, J. Mark Skehel, Stephen C. West, Nature 456, 357 - 361 (20 Nov 2008), doi: 10.1038/nature07470,


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CREG1 (NM_003851) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP750059 Purified recombinant protein of Human cellular repressor of E1A-stimulated genes 1 (CREG1), full length, with N-terminal HIS tag, expressed in E. coli, 100ug, 100 ug (Larger pack size?) ¥3791.00 现货
TA50011-100 4C5, Anti-DDK monoclonal antibody (100 μL) ¥1000 现货
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Also for CREG1 (NM_003851)

OriGene Data
Species:Human Expression Host:E.coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC201654, encoding human full-length CREG1
Tag:N-terminal HIS Predicted MW:23.9 kDa
Purity:> 90% as determined by SDS-PAGE and Coomassie blue staining
Concentration:>50 ug/mL as determined by microplate BCA method
Buffer:The Product was lyophilized from a sterile solution of 1 x PBS, PH7.4.
Protein Families: Secreted Protein
Transmembrane
Transcription Factors
Protein Data
  Protein Image
 

Reference Data
RefSeq: NP_003842 RefSeq Size: 2048 RefSeq ORF: 663
LocusID: 8804 Cytogenetic: 1q24.2  
Synonyms : CREG
Summary: The adenovirus E1A protein both activates and represses gene expression to promote cellular proliferation and inhibit differentiation. The protein encoded by this gene antagonizes transcriptional activation and cellular transformation by E1A. This protein shares limited sequence similarity with E1A and binds both the general transcription factor TBP and the tumor suppressor pRb in vitro. This gene may contribute to the transcriptional control of cell growth and differentiation. [provided by RefSeq, Jul 2008]
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag? is a registered trademark of Sigma-Aldrich

 

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