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OriGene proteins in recent publications

Fully functional proteins purified from transient TrueORF cDNA clone transfections.  Researchers purified GEN1 protein using anti-FLAG M2 affinity column and determined it resolved Holliday junction X0 efficiently in vitro, thus confirming GEN1 is human Holliday junction resolvase.

Identification of Holliday junction resolvases from humans and yeast, Stephen C. Y. Ip, Ulrich Rass, Miguel G. Blanco, Helen R. Flynn, J. Mark Skehel, Stephen C. West, Nature 456, 357 - 361 (20 Nov 2008), doi: 10.1038/nature07470,


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IL2 (NM_000586) Purified Human Protein

Specifications Citations Customer Service Product Documents
Cat. No. Description Datasheet Price Availability*  
TP750020 Purified recombinant protein of Homo sapiens Interleukin 2 (IL-2) produced in E. coli., 100 ug (Larger pack size?) ¥3791.00 现货
TA50011-100 4C5, Anti-DDK monoclonal antibody (100 μL) ¥1000 现货
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OriGene Data
Species:Human Expression Host:E. coli
Expression cDNA Clone or AA Sequence
A DNA sequence from TrueORF clone, RC210013, encoding the region (Ala21-Thr153) of Homo sapiens Interleukin 2 and the molecule has serine substituted for cysteine at amino acid position 125
Tag:Tag-free Predicted MW:15.5 kDa
Purity:>95% as determined by SDS-PAGE and Coomassie blue staining
Concentration:Resuspend the protein to the desired concentration in proper buffer.
Buffer:Lyophilized from a sterile MiliQ-water containing Trehalose, pH7.0. Stable for at least 6 months from date of receipt under proper storage and handling conditions.
Endotoxin: <0.1 EU per 1 ?g of the protein by the LAL
Protein Families: Secreted Protein
Druggable Genome
Protein Pathways: Cytokine-cytokine receptor interaction
Jak-STAT signaling pathway
T cell receptor signaling pathway
Type I diabetes mellitus
Autoimmune thyroid disease
Allograft rejection
More Pathways >>
Protein Data
  Protein Image
 

Reference Data
RefSeq: NP_000577 RefSeq Size: 1047 RefSeq ORF: 462
LocusID: 3558 Cytogenetic: 4q27  
Synonyms : IL-2; lymphokine; TCGF
Summary: Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. [UniProtKB/Swiss-Prot Function]
*: Inventory for certain proteins may be limited due to low expression level. Delivery time may vary from web posted schedule. Contact techsupport@origene.com for specific inventory information
**: DDK-tag is the same as FLAG tag. Flag? is a registered trademark of Sigma-Aldrich

 

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