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OriGene联合CELL杂志共同出版的
CRISPR论文集
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OriGene cDNA clones in recent publications
Epilepsy-associated GRIN2A mutations reduce NMDA receptor trafficking and agonist potency - molecular profiling and functional rescue Sci Rep 2017 [GRIN2A]

Matrix metalloproteinase processing of PTHrP yields a selective regulator of osteogenesis, PTHrP1-17 Oncogene 2017 [PTH1R]

Whole-Exome Sequencing of Congenital Glaucoma Patients Reveals Hypermorphic Variants in GPATCH3, a New Gene Involved in Ocular and Craniofacial Development. Sci Rep 2017 [GPATCH3]

Ziploc-ing the Structure 2.0: endoplasmic reticulum resident peptidyl prolyl isomerases show different activities toward hydroxyproline J. Biol. Chem. 2017 [FKBP2]

TrueORF Gold

HDAC9 (NM_178423) Human cDNA ORF Clone

Specifications Related Products Product Manual FAQs
Cat. No. Description Amount Price Ship Date  
RC218061 HDAC9 (Myc-DDK-tagged)-Human histone deacetylase 9 (HDAC9), transcript variant 4 10 ug
¥15,105.00
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PS100001 pCMV6-Entry, mammalian vector with C-terminal Myc- DDK Tag, 10ug 10 ug ¥3420.00
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Variant Gene Synthesis Stable Cell Line Service

OriGene TrueORF Data
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Vector: pCMV6 Entry Tag: C-terminal MYC/DDK
Western validation with an anti-DDK antibody *
L: Control HEK293 lysate
R: Over-expression lysate
Lysate_Image
Sequence Data: ORF Nucleotide Sequence
Protein Sequence
ORF Size: 3201 bp
Predicted Protein MW: 117 kDa
Restriction Sites: SgfI-MluI     Cloning Scheme for this gene
OTI Annotation: This clone was engineered to express the complete ORF with an expression tag. Expression varies depending on the nature of the gene.
OTI Disclaimer: The molecular sequence of this clone aligns with the gene accession number as a point of reference only. However, individual transcript sequences of the same gene can differ through naturally occurring variations (e.g. polymorphisms), each with its own valid existence. This clone is substantially in agreement with the reference, but a complete review of all prevailing variants is recommended prior to use. More info
Product Components: The ORF clone is ion-exchange column purified, transfection-ready dried plasmid DNA, and shipped with 2 vector sequencing primers.
Protein Families: Transcription Factors
Druggable Genome
* The lysates used for this WB picture contain the overexpressed empty vector or the Myc-DDK tagged ORF clone.

Reference Data
RefSeq: NM_178423.1, NP_848510
RefSeq Size: 4659 RefSeq ORF: 3201
Synonyms : HD7; HD7b; HD9; HDAC; HDAC7; HDAC7B; HDAC9B; HDAC9FL; HDRP; MITR
LocusID: 9734 Cytogenetic: 7p21.1
Summary: Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined. [provided by RefSeq, Jul 2008].

 

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