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Proteins

Recombinant Proteins

Human

Mouse

Rat

Escherichia coli

Blomia tropicalis

SARS-CoV-2

Dermatophagoides pteronyssinus

Streptococcus Pyogenes

Staphylococcus aureus

Orf Virus

Bovine

Dermatophagoides farinae

Rabbit

Streptococcus sp.

Alternaria alternata

Betula pendula

E.coli

Enterobacteria phage T4

Escherichia phage T7

HIV

Hepatitis B Virus

Humulus japonicus

Lachnospiraceae bacterium ND2006

Lepidoglyphus destructor

Leptotrichia wadei

Macaca fascicularis

Mucor hiemalis

Mus musculus

Saccharomyces cerevisiae

Serratia marcescens

Staphylococcus aureus subsp.

Streptomyces avidinii

Streptomyces plicatus

Tobacco etch virus

Vaccinia virus

VEGFA

TNF ALPHA

FGF2

IL6

IGF1

IL33

PTPRN

BDNF

EOTAXIN 3

FGF1

IL1 BETA

IL4

NFYA

NRG1

ALPHA SYNUCLEIN

BMP2

BNP

CSF2

EGF

FABP4

HMG1

LIF

SDF1

CAMK2B

FERRITIN HEAVY CHAIN

FSTL1

GABARAP

HIP2

IL13

IL1B

IL22

IL3

IL8

INTERFERON ALPHA 2

MIF

PDGF AA

SONIC HEDGEHOG

SUMO 3

TGIF

TNF

TRAIL

TRIM72

APOLIPOPROTEIN E

BIRC5

BLNK

CNTF

DESMIN

GDNF

GLUTAMINE SYNTHETASE

IL15

MAP1LC3A

NEUROTROPHIN 3

NHP2

PDGFA

S100A8

TXN

ADIPOQ

AMPHIREGULIN

ANNEXIN V

ANNEXIN VI

APE1

ASB13

ASF1A

ASS1

BETA ARRESTIN 1

BID

BMP4

CALCITONIN

CALRETICULIN 3

CASPASE 10

CSNK1G2

CSPS

CXCL14

CYSTATIN A

EGR1

EIF1A

EIF4E

EIF4EBP1

FGF21

FIBRONECTIN

GABARAPL1

GADD45B

GLUTATHIONE TRANSFERASE ZETA 1

HAO1

HIST1H2AK

IL17

IL17F

IL1RA

IL2

IL7

INHIBIN BETA C CHAIN

INTERFERON GAMMA

KGF

KLF6

KPNA2

LACTB2

LAP2

LEPTIN

LSM4

LYSOPHOSPHOLIPASE 1

HEK293T

HEK293

E. coli

CHO

Sf9

Insect

Baculovirus

Pichia

Pichia pastoris

Mouse

Other

S. cerevisiae

Sf9 insect

H. vulgare

Human

Yeast

N-His

Tag Free

N-GST and C-His

C-His

N-GST and C-HIS

N-GST

N-His-ABP (Albumin-Binding Protein)

His-tag

N-His&C-His

N-His-Trx

N-T7&C-His

N-Trx&His

N-GST, C-His

N-HIS

Tag-free

N-6His

N-GST&His

N-His&SUMO

N-His PDCD1(Pro21-Val170)

N-His-GST

C-Avi&6His

C-HIS

His-tagged, myc-tagged

N-Avi

N-His&C-Fc

N-His&T7

N-MARI

N-Trx

Myc-DDK

N-His-PDCD1(Pro21-Val170)

N-terminal His

N-terminal His-PDCD1(Pro21-Val170) tag

C-DDK

C-DDK-His

C-HIS/C

C-Myc/DDK

DDK-tag

His tag

N-AVI

N-DDK

N-FUSION

N-GFP

N-GST(CKM) and N-His(CKB)

N-HIS and C-AVIPLUS

N-PROTEIN

N-T7

N-TRX

N-TRXA

N-Trx-His

N-terminal His-tag

Druggable Genome

Secreted Protein

Transcription Factors

Transmembrane

ES Cell Differentiation/IPS

Protein Kinase

Stem cell - Pluripotency

Protease

Adult stem cells

Embryonic stem cells

Phosphatase

Induced pluripotent stem cells

Ion Channels: Other

Cancer stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

10 mM Tris-HCl

GPCR

Nuclear Hormone Receptor

the solution can be further dialyzed against PBS (phosphate buffered saline

2 mM dithiothreitol

ELISA.
Western Blot.

e.g. Dulbecco's PBS).

Ion Channels: Potassium

both dissolved in 9.5 M urea buffer (see above). Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml

P450

pH 7.4). For immunization purposes

Ion Channels: Transient receptor potential

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml

pH 7.4).
For immunization purposes

pH 7.4).
For immunization purposes

Ion Channels: Cys-loop Receptors

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoblotting.
Receptor-binding studies.

Western Blot.

0.1% (w/v) insulin

10mM Tris-HCl

1mM DTT

2 mM dithiothreitol

2mM EDTA.
2. Add 4ug of recombinant thioredoxin into reaction cocktail and mix immediately.
3. Incubate at 25°C for 20 minutes.
4. Record the increase in A650nm for 15 minutes

2mM dithiothreitol

63mM sodium phosphate

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: After vimentin is dissolved in 9.5M Urea buffer (see above)

Can be used as standard in a Sandwich ELISA.

Ion Channels: Sodium

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments: after desmin is dissolved in 9.5 M urea buffer (see above)

Protocol: Activity Assay
1. Prepare a 1 ml reaction cocktail into a suitable container: The final concentrations are 5mM Tris

both dissolved in 9.5 M urea buffer (see above).
Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl

e.g. Dulbeccos PBS).

e.g.Dulbecco's PBS).

protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M Urea and then to low salt condition (50mM NaCl

protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4M urea and then to low salt condition (50 mM NaCl

the solution can be further dialyzed against PBS (Phosphate Buffered Saline

ELISA.
Western blotting.

Positive control for Western blot analysis.
Standard for ELISA.

Adermann K. Role of the prosequence of guanylin. Protein Sci. 1999 Sep; 8(9): 1850-9.
4. Lauber T

Cohen MB. Proguanylin secretion and the role of negative-feedback inhibition in a villous epithelial cell line. Am J Physiol Gastrointest Liver Physiol. 2002 Sep; 283(3): G695-702.
3. Schulz A

ELISA

ELISA.
Western blotting.

Forssmann WG

Hawkins JA

Hidaka Y

Ion Channels: ATP Receptors

Marx UC

Marx UC. Native and recombinant proguanylin feature identical biophysical properties and are monomeric in solution. Biochemistry. 2002 Dec 10; 41(49): 14602-12.
2. Rudolph JA

Marx UC. Solution structure of human proguanylin: the role of a hormone prosequence. J Biol Chem. 2003 Jun 27; 278(26): 24118-24. Epub 2003 Apr 21.

Neudecker P

Nourse A

Rosch P

Schulz A

Shimonishi Y

Western Blot.
Protocol: 1. Lauber T

Western Blotting.

Metabolic pathways

Cytokine-cytokine receptor interaction

Pathways in cancer

MAPK signaling pathway

Jak-STAT signaling pathway

Hematopoietic cell lineage

Chemokine signaling pathway

Focal adhesion

Regulation of actin cytoskeleton

Melanoma

Toll-like receptor signaling pathway

Apoptosis

Natural killer cell mediated cytotoxicity

T cell receptor signaling pathway

NOD-like receptor signaling pathway

Alzheimer's disease

Systemic lupus erythematosus

Prostate cancer

Ubiquitin mediated proteolysis

TGF-beta signaling pathway

Fc epsilon RI signaling pathway

Neurotrophin signaling pathway

ErbB signaling pathway

Wnt signaling pathway

Cell cycle

Hypertrophic cardiomyopathy (HCM)

Cytosolic DNA-sensing pathway

Type I diabetes mellitus

Huntington's disease

Glioma

Graft-versus-host disease

Parkinson's disease

Oocyte meiosis

p53 signaling pathway

Dilated cardiomyopathy

RIG-I-like receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

Renal cell carcinoma

Melanogenesis

Pancreatic cancer

Insulin signaling pathway

Prion diseases

Acute myeloid leukemia

Adipocytokine signaling pathway

Colorectal cancer

Hedgehog signaling pathway

Small cell lung cancer

mTOR signaling pathway

Asthma

Pyrimidine metabolism

Chronic myeloid leukemia

PPAR signaling pathway

Endocytosis

Gap junction

Allograft rejection

Bladder cancer

B cell receptor signaling pathway

Purine metabolism

Ribosome

Basal cell carcinoma

Progesterone-mediated oocyte maturation

Base excision repair

Leukocyte transendothelial migration

Regulation of autophagy

Arginine and proline metabolism

Calcium signaling pathway

Nitrogen metabolism

Antigen processing and presentation

Type II diabetes mellitus

VEGF signaling pathway

GnRH signaling pathway

Axon guidance

Glycolysis / Gluconeogenesis

Autoimmune thyroid disease

Long-term potentiation

Spliceosome

Adherens junction

Epithelial cell signaling in Helicobacter pylori infection

Endometrial cancer

Vascular smooth muscle contraction

Oxidative phosphorylation

Cell adhesion molecules (CAMs)

Complement and coagulation cascades

Long-term depression

Neuroactive ligand-receptor interaction

Tyrosine metabolism

ECM-receptor interaction

Non-small cell lung cancer

Phenylalanine metabolism

Amino sugar and nucleotide sugar metabolism

Drug metabolism - other enzymes

Fc gamma R-mediated phagocytosis

Fructose and mannose metabolism

Glutathione metabolism

Porphyrin and chlorophyll metabolism

Primary immunodeficiency

Glycine

Metabolism of xenobiotics by cytochrome P450

Tryptophan metabolism

serine and threonine metabolism

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Cysteine and methionine metabolism

Glycerophospholipid metabolism

SNARE interactions in vesicular transport

Alanine

Cardiac muscle contraction

Pathogenic Escherichia coli infection

RNA degradation

aspartate and glutamate metabolism

Sulfur metabolism

Mismatch repair

Nucleotide excision repair

Olfactory transduction

Pyruvate metabolism

Thyroid cancer

Tight junction

ABC transporters

Viral myocarditis

Homologous recombination

Inositol phosphate metabolism

Retinol metabolism

Aminoacyl-tRNA biosynthesis

DNA replication

Dorso-ventral axis formation

Drug metabolism - cytochrome P450

Glyoxylate and dicarboxylate metabolism

Notch signaling pathway

Phosphatidylinositol signaling system

Terpenoid backbone biosynthesis

Androgen and estrogen metabolism

Arachidonic acid metabolism

Basal transcription factors

Citrate cycle (TCA cycle)

Propanoate metabolism

Butanoate metabolism

Fatty acid metabolism

Lysosome

Maturity onset diabetes of the young

Pantothenate and CoA biosynthesis

Valine

Ether lipid metabolism

Lysine degradation

Methane metabolism

Proteasome

beta-Alanine metabolism

leucine and isoleucine degradation

Galactose metabolism

N-Glycan biosynthesis

Nicotinate and nicotinamide metabolism

One carbon pool by folate

Pentose and glucuronate interconversions

Pentose phosphate pathway

Renin-angiotensin system

Selenoamino acid metabolism

Synthesis and degradation of ketone bodies

Ubiquinone and other terpenoid-quinone biosynthesis

Riboflavin metabolism

Vibrio cholerae infection

Glycosphingolipid biosynthesis - lacto and neolacto series

Heparan sulfate biosynthesis

Phenylalanine

Sphingolipid metabolism

Steroid biosynthesis

tyrosine and tryptophan biosynthesis

C21-Steroid hormone metabolism

Chondroitin sulfate biosynthesis

Histidine metabolism

Keratan sulfate biosynthesis

Linoleic acid metabolism

Non-homologous end-joining

O-Glycan biosynthesis

Primary bile acid biosynthesis

Starch and sucrose metabolism

Taste transduction

alpha-Linolenic acid metabolism

Circadian rhythm - mammal

D-Arginine and D-ornithine metabolism

Folate biosynthesis

RNA polymerase

Taurine and hypotaurine metabolism

Caffeine metabolism

D-Glutamine and D-glutamate metabolism

Glycosaminoglycan degradation

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Limonene and pinene degradation

Other glycan degradation

leucine and isoleucine biosynthesis

Ascorbate and aldarate metabolism

Biosynthesis of unsaturated fatty acids

Cyanoamino acid metabolism

Fatty acid elongation in mitochondria

Glycerolipid metabolism

Glycosphingolipid biosynthesis - ganglio series

Lipoic acid metabolism

Protein export

1

2

3

Yes

In Stock