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MLH1 Mutant (K618E), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | K618E |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Products
MSH6 Mutant (Y1256X), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 6 (E. coli) (MSH6) as transfection-ready DNA
| Mutation | Y1256X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (L550P), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | L550P |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BRAF Mutant (E501v), Myc-DDK-tagged ORF clone of Homo sapiens v-raf murine sarcoma viral oncogene homolog B1 (BRAF) as transfection-ready DNA
| Mutation | E501v |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (Q301X), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | Q301X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH2 Mutant (G162R), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) as transfection-ready DNA
| Mutation | G162R |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH6 Mutant (E1163V), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 6 (E. coli) (MSH6) as transfection-ready DNA
| Mutation | E1163V |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
EGFR Mutant (L747_T751del), Myc-DDK-tagged ORF clone of Homo sapiens epidermal growth factor receptor (EGFR), transcript variant 1 as transfection-ready DNA
| Mutation | L747_T751del |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH2 Mutant (G204X), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) as transfection-ready DNA
| Mutation | G204X |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH2 Mutant (A636P), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) as transfection-ready DNA
| Mutation | A636P |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH6 Mutant (R1076C), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 6 (E. coli) (MSH6) as transfection-ready DNA
| Mutation | R1076C |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (V384D), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | V384D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (S406N), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | S406N |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MSH2 Mutant (K931T), Myc-DDK-tagged ORF clone of Homo sapiens mutS homolog 2, colon cancer, nonpolyposis type 1 (E. coli) (MSH2) as transfection-ready DNA
| Mutation | K931T |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MLH1 Mutant (E663A), Myc-DDK-tagged ORF clone of Homo sapiens mutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli) (MLH1), transcript variant 1 as transfection-ready DNA
| Mutation | E663A |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
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Species
Target Symbol
- MLH1 (246)
- MSH2 (215)
- P53 (148)
- MSH6 (91)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (69)
- EGFR (49)
- BRAF (34)
- CTNNB1 (32)
- KRAS (23)
- RAF1 (19)
- TCF7L2 (19)
- BETA CATENIN (17)
- MET (15)
- BAX (14)
- B RAF (11)
- PIK3R5 (10)
- RALGDS (9)
- TCF7 (9)
- JNK1 (8)
- JNK2 (8)
- MAP2K1 (7)
- PI 3 KINASE P85 ALPHA (7)
- ACTIVIN A RECEPTOR TYPE IC (6)
- AKT1 (6)
- PI 3 KINASE P55 GAMMA (6)
- SMAD3 (6)
- A RAF (5)
- ACTIVIN A RECEPTOR TYPE IB (5)
- AKT2 (5)
- AKT3 (5)
- APC (5)
- AXIN1 (5)
- JNK3 (5)
- LEF1 (5)
- PI 3 KINASE CATALYTIC SUBUNIT GAMMA (5)
- CASPASE 9 (4)
- FRIZZLED 6 (4)
- FZD3 (4)
- IGF1 RECEPTOR (4)
- MEK1 (4)
- PIK3CB (4)
- AXIN2 (3)
- BCL2 (3)
- BIRC5 (3)
- CASPASE 3 (3)
- ERK1 (3)
- ERK2 (3)
- SMAD2 (3)
- TGF BETA RECEPTOR I (3)
- TGF BETA RECEPTOR II (3)
- AXIN 1 (2)
- BAD (2)
- DCC (2)
- DISHEVELLED 3 (2)
- DVL1 (2)
- FRIZZLED 2 (2)
- FRIZZLED 7 (2)
- FRIZZLED 8 (2)
- FRIZZLED HOMOLOG 1 (2)
- GRB2 (2)
- GSK3 BETA (2)
- MYC (2)
- PDGF RECEPTOR ALPHA (2)
- PDGF RECEPTOR BETA (2)
- PI 3 KINASE P85 BETA (2)
- RAC1 (2)
- RAC2 (2)
- SOS1 (2)
- SOS2 (2)
- TCF7L1 (2)
- TGF BETA 1 (2)
- TGF BETA 2 (2)
- APPL (1)
- AXIN 2 (1)
- C FOS (1)
- C-JUN (1)
- C-MYC (1)
- CYCLIN D1 (1)
- CYTOCHROME C (1)
- DISHEVELLED 2 (1)
- FRIZZLED 10 (1)
- FRIZZLED 4 (1)
- FRIZZLED 5 (1)
- FRIZZLED 9 (1)
- MSH3 (1)
- PIK3CD (1)
- RAC3 (1)
- SMAD4 (1)
- TGF BETA 3 (1)
Vectors
Families
- Druggable Genome (1229)
- Stem cell - Pluripotency (469)
- Transcription Factors (249)
- Protein Kinase (214)
- ES Cell Differentiation/IPS (190)
- Transmembrane (131)
- Stem cell relevant signaling - JAK/STAT signaling pathway (62)
- Cancer stem cells (58)
- Adult stem cells (54)
- Secreted Protein (54)
- GPCR (16)
- Embryonic stem cells (12)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (12)
- Stem cell relevant signaling - Wnt Signaling pathway (11)
- Induced pluripotent stem cells (7)
- Protease (7)
- Stem cell relevant signaling - DSL/Notch pathway (1)
