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CTNNB1 Mutant (S45Y), Myc-DDK-tagged ORF clone of Homo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1 as transfection-ready DNA
| Mutation | S45Y |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
Products
WDR3 (Myc-DDK-tagged)-Human WD repeat domain 3 (WDR3)
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-AC-Myc-DDK |
- TrueORF®
MET Mutant (E168D), Myc-DDK-tagged ORF clone of Homo sapiens met proto-oncogene (hepatocyte growth factor receptor) (MET), transcript variant 2 as transfection-ready DNA
| Mutation | E168D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CTNNB1 Mutant (A5_Q143del), Myc-DDK-tagged ORF clone of Homo sapiens anaplastic lymphoma receptor tyrosine kinase (ALK) as transfection-ready DNA
| Mutation | A5_Q143del |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MET Mutant (M1250T), Myc-DDK-tagged ORF clone of Homo sapiens met proto-oncogene (hepatocyte growth factor receptor) (MET), transcript variant 2 as transfection-ready DNA
| Mutation | M1250T |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
EPHA7 (DDK-His-tagged)-Extra Cellular Domain Clone of Homo sapiens EPH receptor A7, Signal peptide (1-27) plus EC domain (28-555)
| Type | Human Tagged ORF Clone |
| Tag | DDK-His |
| Vector | pCMV6-XL5-DDK-His |
- TrueORF®
ACVR1 Mutant (G328R), Myc-DDK-tagged ORF clone of Homo sapiens activin A receptor, type I (ACVR1), transcript variant 1 as transfection-ready DNA
| Mutation | G328R |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
BUB1B Mutant (R550Q), Myc-DDK-tagged ORF clone of Homo sapiens budding uninhibited by benzimidazoles 1 homolog beta (yeast) (BUB1B) as transfection-ready DNA
| Mutation | R550Q |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
ACVR1 Mutant (G356D), Myc-DDK-tagged ORF clone of Homo sapiens activin A receptor, type I (ACVR1), transcript variant 1 as transfection-ready DNA
| Mutation | G356D |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
ILK Mutant (A262V), Myc-DDK-tagged ORF clone of Homo sapiens integrin-linked kinase (ILK), transcript variant 1 as transfection-ready DNA
| Mutation | A262V |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
WDFY3 (Myc-DDK-tagged)-Human WD repeat and FYVE domain containing 3 (WDFY3)
| Type | Human Tagged ORF Clone |
| Tag | Myc-DDK |
| Vector | pCMV6-AC-Myc-DDK |
- TrueORF®
MET Mutant (R970C), Myc-DDK-tagged ORF clone of Homo sapiens met proto-oncogene (hepatocyte growth factor receptor) (MET), transcript variant 2 as transfection-ready DNA
| Mutation | R970C |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CTNNB1 Mutant (S45A), Myc-DDK-tagged ORF clone of Homo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1 as transfection-ready DNA
| Mutation | S45A |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
CTNNB1 Mutant (D32N), Myc-DDK-tagged ORF clone of Homo sapiens catenin (cadherin-associated protein), beta 1, 88kDa (CTNNB1), transcript variant 1 as transfection-ready DNA
| Mutation | D32N |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
MET Mutant (T1173I), Myc-DDK-tagged ORF clone of Homo sapiens met proto-oncogene (hepatocyte growth factor receptor) (MET), transcript variant 2 as transfection-ready DNA
| Mutation | T1173I |
| Tag | Myc-DDK |
| Vector | pCMV6-Entry |
- TrueORF®
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Species
Target Symbol
- P53 (99)
- EGFR (31)
- KRAS (22)
- VEGFA (22)
- PLAGL1 (20)
- CD44 (19)
- CD46 (17)
- KCNJ15 (16)
- MET (16)
- BETA CATENIN (15)
- DISC1 (15)
- ALPHA DYSTROGLYCAN (14)
- BDNF (14)
- HNF 4 ALPHA (14)
- MORTALITY FACTOR 4 LIKE 2 (14)
- NRAS (14)
- SLC16A3 (14)
- SPHK1 (14)
- CEACAM1 (13)
- MYADM (13)
- PI 3 KINASE CATALYTIC SUBUNIT ALPHA (13)
- RHOH (13)
- RUNX1T1 (13)
- TFEB (13)
- FGFR1 (12)
- FGFR2 (12)
- HEXIM2 (12)
- MID1 (12)
- MU OPIOID RECEPTOR (12)
- PTGER3 (12)
- SYNTABULIN (12)
- YAP1 (12)
- B RAF (11)
- BHLHB9 (11)
- CCR6 (11)
- DNMT3B (11)
- EIF5A (11)
- ESTROGEN RELATED RECEPTOR GAMMA (11)
- IL1RAP (11)
- ISLR2 (11)
- NRG1 (11)
- PAX6 (11)
- PEX2 (11)
- RNF146 (11)
- RUNX2 (11)
- STEAP2 (11)
- BIN1 (10)
- CAMK2G (10)
- CD36 (10)
- CD82 (10)
- FGFR3 (10)
- FIGNL1 (10)
- GAPDH (10)
- IGF2 (10)
- KCNE1 (10)
- LAMP2 (10)
- MAX (10)
- MEF2C (10)
- MUSK (10)
- PMP22 (10)
- RAB23 (10)
- RET (10)
- SLITRK2 (10)
- SOCS2 (10)
- TGIF (10)
- TJAP1 (10)
- TMEM9 (10)
- ANO6 (9)
- C11ORF51 (9)
- C19ORF48 (9)
- CAMK2B (9)
- CAMK2D (9)
- CARHSP1 (9)
- CTNND1 (9)
- DAG1 (9)
- FAM156A (9)
- FGF1 (9)
- FUT7 (9)
- GLUCOCORTICOID RECEPTOR (9)
- GPR19 (9)
- GROWTH HORMONE RECEPTOR (9)
- HHAT (9)
- HSD17B13 (9)
- IFI27 (9)
- KCNJ1 (9)
- KCNK2 (9)
- LY6E (9)
- MIER1 (9)
- MITF (9)
- NF2 (9)
- NRP2 (9)
- NUMB (9)
- P21 RAS (9)
- P311 (9)
- PITX2 (9)
- SIRT3 (9)
- SSH3BP1 (9)
- TAU (9)
- TOR1AIP2 (9)
- TRP63 (9)
Vectors
Mutants
Families
- Druggable Genome (10077)
- Transmembrane (6703)
- Transcription Factors (2741)
- Secreted Protein (1651)
- Protein Kinase (923)
- ES Cell Differentiation/IPS (666)
- Protease (570)
- GPCR (562)
- Stem cell - Pluripotency (546)
- Phosphatase (242)
- Ion Channels: Other (190)
- Adult stem cells (174)
- Nuclear Hormone Receptor (138)
- Ion Channels: Potassium (126)
- Embryonic stem cells (125)
- Cancer stem cells (100)
- Ion Channels: Cys-loop Receptors (75)
- P450 (68)
- Induced pluripotent stem cells (65)
- Stem cell relevant signaling - JAK/STAT signaling pathway (60)
- Ion Channels: Transient receptor potential (43)
- Stem cell relevant signaling - DSL/Notch pathway (40)
- Ion Channels: Glutamate Receptors (34)
- Stem cell relevant signaling - TGFb/BMP signaling pathway (34)
- Ion Channels: Sodium (27)
- Stem cell relevant signaling - Wnt Signaling pathway (26)
- Ion Channels: Calcium (22)
- Ion Channels: Cyclic nucleotide gated (13)
- Ion Channels: ATP Receptors (11)
Pathways
- Metabolic pathways (1364)
- Pathways in cancer (853)
- MAPK signaling pathway (657)
- Neuroactive ligand-receptor interaction (487)
- Cytokine-cytokine receptor interaction (474)
- Focal adhesion (416)
- Regulation of actin cytoskeleton (413)
- Neurotrophin signaling pathway (402)
- Prostate cancer (385)
- Wnt signaling pathway (365)
- Olfactory transduction (358)
- Colorectal cancer (354)
- Chemokine signaling pathway (352)
- Calcium signaling pathway (346)
- Endocytosis (336)
- Huntington's disease (335)
- Melanoma (335)
- Pancreatic cancer (320)
- Glioma (310)
- Endometrial cancer (300)
- Chronic myeloid leukemia (296)
- Cell cycle (292)
- Apoptosis (289)
- Natural killer cell mediated cytotoxicity (287)
- Insulin signaling pathway (278)
- ErbB signaling pathway (277)
- Non-small cell lung cancer (276)
- Jak-STAT signaling pathway (272)
- Bladder cancer (267)
- Axon guidance (265)
- Alzheimer's disease (249)
- T cell receptor signaling pathway (245)
- Small cell lung cancer (244)
- Tight junction (242)
- GnRH signaling pathway (240)
- Melanogenesis (239)
- p53 signaling pathway (235)
- Progesterone-mediated oocyte maturation (233)
- Thyroid cancer (225)
- Ubiquitin mediated proteolysis (223)
- Cell adhesion molecules (CAMs) (222)
- Purine metabolism (218)
- Renal cell carcinoma (217)
- Gap junction (213)
- Leukocyte transendothelial migration (210)
- Adherens junction (208)
- Amyotrophic lateral sclerosis (ALS) (204)
- VEGF signaling pathway (204)
- Oocyte meiosis (200)
- Basal cell carcinoma (198)
- Toll-like receptor signaling pathway (194)
- Vascular smooth muscle contraction (192)
- Acute myeloid leukemia (187)
- B cell receptor signaling pathway (185)
- Fc epsilon RI signaling pathway (178)
- Long-term potentiation (176)
- Fc gamma R-mediated phagocytosis (174)
- Hematopoietic cell lineage (166)
- Long-term depression (165)
- Dilated cardiomyopathy (157)
- Parkinson's disease (155)
- Systemic lupus erythematosus (152)
- Lysosome (149)
- Arrhythmogenic right ventricular cardiomyopathy (ARVC) (142)
- Epithelial cell signaling in Helicobacter pylori infection (141)
- Pyrimidine metabolism (137)
- Hypertrophic cardiomyopathy (HCM) (136)
- Viral myocarditis (135)
- TGF-beta signaling pathway (134)
- mTOR signaling pathway (134)
- ECM-receptor interaction (133)
- Oxidative phosphorylation (133)
- Spliceosome (133)
- Adipocytokine signaling pathway (128)
- NOD-like receptor signaling pathway (125)
- Type II diabetes mellitus (119)
- Antigen processing and presentation (118)
- PPAR signaling pathway (116)
- Complement and coagulation cascades (112)
- RIG-I-like receptor signaling pathway (111)
- Phosphatidylinositol signaling system (102)
- Pathogenic Escherichia coli infection (98)
- Cardiac muscle contraction (93)
- Ribosome (89)
- Glycerophospholipid metabolism (86)
- Glycolysis / Gluconeogenesis (86)
- Cytosolic DNA-sensing pathway (83)
- Dorso-ventral axis formation (83)
- Inositol phosphate metabolism (82)
- ABC transporters (81)
- Glutathione metabolism (81)
- Vibrio cholerae infection (81)
- Drug metabolism - cytochrome P450 (79)
- Arachidonic acid metabolism (77)
- Hedgehog signaling pathway (77)
- Taste transduction (76)
- Autoimmune thyroid disease (72)
- Metabolism of xenobiotics by cytochrome P450 (72)
- Notch signaling pathway (72)
- Type I diabetes mellitus (72)
- Retinol metabolism (70)
- RNA degradation (69)
- Arginine and proline metabolism (68)
- N-Glycan biosynthesis (68)
- Primary immunodeficiency (66)
- Graft-versus-host disease (64)
- Tyrosine metabolism (64)
- Lysine degradation (61)
- Valine (61)
- Prion diseases (60)
- Sphingolipid metabolism (60)
- Allograft rejection (59)
- Maturity onset diabetes of the young (59)
- Drug metabolism - other enzymes (58)
- Cysteine and methionine metabolism (56)
- Glycerolipid metabolism (56)
- Pyruvate metabolism (56)
- Fatty acid metabolism (55)
- Base excision repair (52)
- leucine and isoleucine degradation (52)
- SNARE interactions in vesicular transport (50)
- Starch and sucrose metabolism (50)
- Amino sugar and nucleotide sugar metabolism (48)
- Ether lipid metabolism (48)
- Homologous recombination (48)
- Nucleotide excision repair (48)
- Proteasome (47)
- Tryptophan metabolism (46)
- Alanine (45)
- Androgen and estrogen metabolism (45)
- aspartate and glutamate metabolism (45)
- Aminoacyl-tRNA biosynthesis (43)
- Citrate cycle (TCA cycle) (43)
- Fructose and mannose metabolism (42)
- Porphyrin and chlorophyll metabolism (41)
- Nicotinate and nicotinamide metabolism (40)
- Asthma (38)
- DNA replication (38)
- Galactose metabolism (37)
- Propanoate metabolism (37)
- Regulation of autophagy (37)
- RNA polymerase (36)
- Glycosphingolipid biosynthesis - lacto and neolacto series (35)
- Glycine (34)
- serine and threonine metabolism (34)
- Butanoate metabolism (33)
- Glycosaminoglycan degradation (33)
- Phenylalanine metabolism (33)
- Selenoamino acid metabolism (33)
- Basal transcription factors (32)
- Linoleic acid metabolism (30)
- Mismatch repair (30)
- Pentose phosphate pathway (30)
- Histidine metabolism (29)
- Nitrogen metabolism (28)
- Non-homologous end-joining (28)
- O-Glycan biosynthesis (28)
- Renin-angiotensin system (27)
- Heparan sulfate biosynthesis (26)
- Chondroitin sulfate biosynthesis (25)
- Circadian rhythm - mammal (23)
- Riboflavin metabolism (23)
- Biosynthesis of unsaturated fatty acids (22)
- Glycosphingolipid biosynthesis - globo series (22)
- Keratan sulfate biosynthesis (22)
- beta-Alanine metabolism (22)
- Glycosphingolipid biosynthesis - ganglio series (21)
- Glycosylphosphatidylinositol(GPI)-anchor biosynthesis (21)
- Pentose and glucuronate interconversions (21)
- Primary bile acid biosynthesis (20)
- Steroid biosynthesis (20)
- One carbon pool by folate (19)
- Other glycan degradation (19)
- Pantothenate and CoA biosynthesis (19)
- alpha-Linolenic acid metabolism (18)
- Ascorbate and aldarate metabolism (17)
- C21-Steroid hormone metabolism (16)
- Glyoxylate and dicarboxylate metabolism (16)
- Sulfur metabolism (16)
- Terpenoid backbone biosynthesis (15)
- Limonene and pinene degradation (14)
- Taurine and hypotaurine metabolism (14)
- leucine and isoleucine biosynthesis (13)
- Cyanoamino acid metabolism (12)
- Synthesis and degradation of ketone bodies (12)
- Caffeine metabolism (11)
- Fatty acid biosynthesis (11)
- Folate biosynthesis (10)
- Phenylalanine (9)
- tyrosine and tryptophan biosynthesis (9)
- Fatty acid elongation in mitochondria (8)
- Protein export (8)
- Lipoic acid metabolism (7)
- Thiamine metabolism (7)
- Methane metabolism (6)
- Ubiquinone and other terpenoid-quinone biosynthesis (6)
- Vitamin B6 metabolism (6)
- Biotin metabolism (5)
- D-Glutamine and D-glutamate metabolism (3)
- Lysine biosynthesis (3)
- O-Mannosyl glycan biosynthesis (3)
