Proteins

Proteins

Recombinant Proteins

Over-expression Lysates

CytoSections

Mass Spec Standards

Mutant CytoSections

Mutant Proteins

Human

FGFR1

AURORA A

CAMK2B

EGFR

AKT1

JNK1

PAK4

NEK6

TRKB

ERBB 3

HER2

JNK2

CAMK2D

CSNK1G3

ROR1

CAMKK

CAMKK2

FYN

P38

PROTEIN KINASE D2

PYK2

B RAF

FGFR4

MCK10

CDK2

DDR2

PCTAIRE1

TRKC

ERK2

MET

ABL2

CCK4

CSK

DYSTROPHIA MYOTONICA PROTEIN KINASE

FGFR3

MATK

RYK

SRC

STK16

ZAK

ACTIVIN RECEPTOR TYPE IA

CAMK1D

CDK6

FAK

FGFR2

JNK3

PDGF RECEPTOR BETA

PRKACA

TIE1

VRK3

AKT3

BMX

CK1 EPSILON

ERBB 4

IRAK

MAPKAP KINASE 2

MSK1

MST4

PKC BETA 1

PKC ZETA

SGK1

TRKA

ACTIVIN A RECEPTOR TYPE IC

ACTIVIN RECEPTOR TYPE IIB

ACVRL1

BMPR2

CAMK2G

CDK1

CHK1

EPH RECEPTOR A2

ERK1

FGR

INTEGRIN LINKED KINASE

LYK5

PKC EPSILON

PKR

PRKACB

SGK3

ACTIVIN RECEPTOR TYPE IIA

ALPK1

CAMK2A

CD117

CDK5

FASTK

FLT1

HCK

HSP22

IRE1

MAP4K5

MCSF RECEPTOR

MEK3

MNK1

NEK11

PAK5

RIOK1

ROR2

TAK1

TGF BETA RECEPTOR II

AXL

CGKI

WB

IHC

HEK293T

HEK293

E. coli

Sf9

Insect

CHO

Baculovirus

C-Myc/DDK

C-MYC/DDK

His-tag

N-His

C-His

C-DDK/His

C-DDK

C-Fc

N-GST and C-His

N-GST and C-HIS

Tag Free

C-6His

C-Fc&His

N-His-ABP (Albumin-Binding Protein)

N-GST

C-6His-Avi

Myc-DDK

N-6His

N-His-SUMO

hIgG-His-tag

C-8His

C-FLAG

C-FLAG-6His

C-Fc-Avi

C-Myc-DDK

C-hFc

C-mFc

N-10His-Flag

N-FUSION

Yes

MVPro

SDS PAGE

Druggable Genome

WB

Transmembrane

Transcription Factors

Secreted Protein

Protein Kinase

ES Cell Differentiation/IPS

Protease

Stem cell - Pluripotency

Phosphatase

GPCR

Ion Channels: Other

Adult stem cells

Embryonic stem cells

Nuclear Hormone Receptor

Cancer stem cells

Induced pluripotent stem cells

P450

Ion Channels: Potassium

Stem cell relevant signaling - JAK/STAT signaling pathway

Stem cell relevant signaling - TGFb/BMP signaling pathway

Stem cell relevant signaling - Wnt Signaling pathway

Stem cell relevant signaling - DSL/Notch pathway

Ion Channels: Cys-loop Receptors

Ion Channels: Transient receptor potential

Ion Channels: Glutamate Receptors

Ion Channels: ATP Receptors

Ion Channels: Sodium

Ion Channels: Cyclic nucleotide gated

Ion Channels: Calcium

ELISA

000) and Immunohistochemistry (1/200-1/1

000) as well as other phosphatase-Biotin/biotin based enzymatic assays.
Assay by Immunoelectrophoresis resulted in a single precipitin arc against anti-Alkaline Phosphatase (calf intestine) and anti-Biotin.

000-1/32

1/500-1/2

10 mM Tris-HCl

2 mM dithiothreitol

500)

ELISA.
Suitable for use as a Control or standard in indirect trapping ELISA for quantitation of antigen in serum using a standard curve.
Immunoprecipitation.
Western blotting.

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.
Protocol: Reconstitution to filaments is performed by mixing equimolar amounts of keratins of type I and type II at concentrations of approx. 0.5 mg/ml

ELISA (1/8

FACS

Protein standard in 1D and 2D SDS gelelectrophoresis.
Immunoassays.
Immunization.

Suitable for Immunoblotting (Western or Dot blot

The DYKDDDDK peptide (Flag) is used as a fusion tag for immunoaffinity chromatography.

both dissolved in 9.5 M urea buffer (see above). Protofilaments and filament complexes are obtained by dialyzing the resulting polypeptide solution stepwise to a concentration of 4 M urea and then to low salt condition (50 mM NaCl

e.g. Dulbecco's PBS).

pH 7.4).
For immunization purposes

the solution can be further dialyzed against PBS (phosphate buffered saline

MAPK signaling pathway

Pathways in cancer

Neurotrophin signaling pathway

ErbB signaling pathway

Focal adhesion

GnRH signaling pathway

Chemokine signaling pathway

Progesterone-mediated oocyte maturation

Regulation of actin cytoskeleton

Insulin signaling pathway

T cell receptor signaling pathway

Fc epsilon RI signaling pathway

Endocytosis

Prostate cancer

Glioma

Colorectal cancer

Pancreatic cancer

Toll-like receptor signaling pathway

Calcium signaling pathway

Wnt signaling pathway

Oocyte meiosis

Axon guidance

Melanoma

Adherens junction

Long-term potentiation

Cytokine-cytokine receptor interaction

Non-small cell lung cancer

Gap junction

VEGF signaling pathway

Epithelial cell signaling in Helicobacter pylori infection

Endometrial cancer

Melanogenesis

Chronic myeloid leukemia

Vascular smooth muscle contraction

Fc gamma R-mediated phagocytosis

mTOR signaling pathway

Renal cell carcinoma

Adipocytokine signaling pathway

Acute myeloid leukemia

Tight junction

Bladder cancer

Natural killer cell mediated cytotoxicity

TGF-beta signaling pathway

NOD-like receptor signaling pathway

B cell receptor signaling pathway

RIG-I-like receptor signaling pathway

Type II diabetes mellitus

Cell cycle

Apoptosis

Long-term depression

Olfactory transduction

Leukocyte transendothelial migration

Hedgehog signaling pathway

Small cell lung cancer

Prion diseases

Thyroid cancer

Jak-STAT signaling pathway

Amyotrophic lateral sclerosis (ALS)

p53 signaling pathway

Alzheimer's disease

Dorso-ventral axis formation

Vibrio cholerae infection

Viral myocarditis

Regulation of autophagy

Pathogenic Escherichia coli infection

Dilated cardiomyopathy

Taste transduction

Hematopoietic cell lineage

Cytosolic DNA-sensing pathway

Primary immunodeficiency

Phosphatidylinositol signaling system

Circadian rhythm - mammal

PPAR signaling pathway

Purine metabolism

Basal cell carcinoma

Hypertrophic cardiomyopathy (HCM)

Ubiquitin mediated proteolysis

Parkinson's disease

Nucleotide excision repair

Basal transcription factors

Human

E. coli

Human 293

1

2

Yes

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