Proteins

Proteins

CytoSections

Human

AMSH

CDC42

FGFR4

GIT2

LDL RECEPTOR

P21 RAS

PIP5K1 ALPHA

TRKA

USP8

ACTIVIN A RECEPTOR TYPE IC

AP2B1

AP2M1

BETA ARRESTIN 1

CBL C

CD71

CXCR2

DYNAMIN 1

EGFR

EPS15

ERBB 3

ERBB 4

FGFR2

GRK6

NEDD4

RET

SH3KBP1

SMURF1

SRC

TRAF6

ACTIVIN A RECEPTOR TYPE IB

ADRB2

ADRB3

ALIX

BETA ARRESTIN 2

BMP2

CBL

CBLB

CCR5

CD117

CHMP1B

CLTCL1

CSF1R

CXCR1

CXCR4

DAB2

DNAJC6

EGF

EHD1

F2R

FGFR3

GIT1

GRK1

GRK2

GRK3

GRK4

GRK5

GRK7

HGS

IGF1R

IL2RA

IL2RB

IL2RG

ITCH

KDR

LDLRAP1

MDM2

MET

NEDD4 2

PAR6

PDGFRA

PIP4K2B

PIP5K1 BETA

PIP5K3

PIP5KI GAMMA

PKC ZETA

PLD2

PRKCI

RAB11A

RAB11B

RAB11FIP1

RAB22A

RAB31

RAB4A

RAB5A

RAB5B

RAB5C

SH3 CONTAINING GRB 2 LIKE 1 PROTEIN

SMURF2

TGF BETA RECEPTOR I

TGF BETA RECEPTOR II

HEK293T

C-Myc/DDK

C-MYC/DDK

His-tag

C-DDK/His

C-DDK

C-His

N-His

Tag Free

C-Fc

N-GST and C-His

T7-tag

hIgG-His-tag

N-GST and C-HIS

Druggable Genome

Transmembrane

Protein Kinase

ES Cell Differentiation/IPS

Transcription Factors

Secreted Protein

Adult stem cells

GPCR

Stem cell - Pluripotency

Protease

Stem cell relevant signaling - JAK/STAT signaling pathway

Cancer stem cells

Embryonic stem cells

Induced pluripotent stem cells

Stem cell relevant signaling - TGFb/BMP signaling pathway

Metabolic pathways

Pathways in cancer

MAPK signaling pathway

Cytokine-cytokine receptor interaction

Neuroactive ligand-receptor interaction

Regulation of actin cytoskeleton

Chemokine signaling pathway

Focal adhesion

Neurotrophin signaling pathway

Calcium signaling pathway

Jak-STAT signaling pathway

Wnt signaling pathway

Insulin signaling pathway

Cell cycle

T cell receptor signaling pathway

Progesterone-mediated oocyte maturation

ErbB signaling pathway

Natural killer cell mediated cytotoxicity

Endocytosis

Purine metabolism

Oocyte meiosis

Apoptosis

Hematopoietic cell lineage

Prostate cancer

Toll-like receptor signaling pathway

Axon guidance

GnRH signaling pathway

Colorectal cancer

Alzheimer's disease

Ubiquitin mediated proteolysis

Melanogenesis

Pancreatic cancer

Adherens junction

Leukocyte transendothelial migration

Tight junction

Vascular smooth muscle contraction

Small cell lung cancer

Gap junction

TGF-beta signaling pathway

Chronic myeloid leukemia

Lysosome

Fc epsilon RI signaling pathway

Huntington's disease

Renal cell carcinoma

Cell adhesion molecules (CAMs)

Dilated cardiomyopathy

Glioma

Melanoma

VEGF signaling pathway

B cell receptor signaling pathway

Hypertrophic cardiomyopathy (HCM)

Acute myeloid leukemia

Adipocytokine signaling pathway

Long-term potentiation

Complement and coagulation cascades

Fc gamma R-mediated phagocytosis

p53 signaling pathway

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Endometrial cancer

NOD-like receptor signaling pathway

Non-small cell lung cancer

Phosphatidylinositol signaling system

Long-term depression

Olfactory transduction

RIG-I-like receptor signaling pathway

Amyotrophic lateral sclerosis (ALS)

Glycolysis / Gluconeogenesis

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

PPAR signaling pathway

Bladder cancer

Inositol phosphate metabolism

Pathogenic Escherichia coli infection

Thyroid cancer

Antigen processing and presentation

Drug metabolism - cytochrome P450

mTOR signaling pathway

Cardiac muscle contraction

Metabolism of xenobiotics by cytochrome P450

Type II diabetes mellitus

Valine

Basal cell carcinoma

Cytosolic DNA-sensing pathway

Hedgehog signaling pathway

Pyrimidine metabolism

Arginine and proline metabolism

Parkinson's disease

Primary immunodeficiency

Retinol metabolism

leucine and isoleucine degradation

Viral myocarditis

Drug metabolism - other enzymes

Glycerophospholipid metabolism

Glycerolipid metabolism

Nucleotide excision repair

Tyrosine metabolism

Base excision repair

Prion diseases

Arachidonic acid metabolism

Fructose and mannose metabolism

Taste transduction

Vibrio cholerae infection

Autoimmune thyroid disease

Pyruvate metabolism

Fatty acid metabolism

SNARE interactions in vesicular transport

Sphingolipid metabolism

Systemic lupus erythematosus

Lysine degradation

Notch signaling pathway

Amino sugar and nucleotide sugar metabolism

Butanoate metabolism

Starch and sucrose metabolism

Galactose metabolism

Glutathione metabolism

Proteasome

Tryptophan metabolism

Androgen and estrogen metabolism

Pentose phosphate pathway

Regulation of autophagy

Alanine

Cysteine and methionine metabolism

Histidine metabolism

aspartate and glutamate metabolism

Linoleic acid metabolism

Propanoate metabolism

Type I diabetes mellitus

Oxidative phosphorylation

Ether lipid metabolism

Homologous recombination

Maturity onset diabetes of the young

Ribosome

Citrate cycle (TCA cycle)

Nitrogen metabolism

Porphyrin and chlorophyll metabolism

Mismatch repair

Aminoacyl-tRNA biosynthesis

Dorso-ventral axis formation

Glycosaminoglycan degradation

Phenylalanine metabolism

Renin-angiotensin system

Spliceosome

beta-Alanine metabolism

Allograft rejection

DNA replication

Pantothenate and CoA biosynthesis

Riboflavin metabolism

ABC transporters

Selenoamino acid metabolism

C21-Steroid hormone metabolism

Other glycan degradation

leucine and isoleucine biosynthesis

Glycine

Non-homologous end-joining

serine and threonine metabolism

Circadian rhythm - mammal

Graft-versus-host disease

Asthma

Folate biosynthesis

N-Glycan biosynthesis

Primary bile acid biosynthesis

alpha-Linolenic acid metabolism

Basal transcription factors

Steroid biosynthesis

Terpenoid backbone biosynthesis

Pentose and glucuronate interconversions

Synthesis and degradation of ketone bodies

Ascorbate and aldarate metabolism

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

RNA degradation

One carbon pool by folate

Thiamine metabolism

Ubiquinone and other terpenoid-quinone biosynthesis

Nicotinate and nicotinamide metabolism

Sulfur metabolism

Biosynthesis of unsaturated fatty acids

Caffeine metabolism

Glycosphingolipid biosynthesis - lacto and neolacto series

Fatty acid elongation in mitochondria

Methane metabolism

Taurine and hypotaurine metabolism

Fatty acid biosynthesis

Glycosphingolipid biosynthesis - ganglio series

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

Phenylalanine

Protein export

RNA polymerase

tyrosine and tryptophan biosynthesis

O-Glycan biosynthesis

Vitamin B6 metabolism

Biotin metabolism

Chondroitin sulfate biosynthesis

D-Arginine and D-ornithine metabolism

D-Glutamine and D-glutamate metabolism

Keratan sulfate biosynthesis

1