Proteins

Proteins

Recombinant Proteins

Over-expression Lysates

Mutant Proteins

Human

P53

FOXO3

B RAF

HER2

E2F1

EGFR

KRAS

NRAS

A RAF

AKT1

AKT3

CDK4

CYCLIN D1

ERK2

GRB2

NORE1

P21 RAS

PDPK1

PI 3 KINASE CATALYTIC SUBUNIT GAMMA

RAF1

RETINOID X RECEPTOR ALPHA

WB

HEK293T

HEK293

C-Myc/DDK

Yes

MVPro

SDS PAGE

Druggable Genome

Protein Kinase

Transcription Factors

Stem cell - Pluripotency

ES Cell Differentiation/IPS

Transmembrane

Stem cell relevant signaling - JAK/STAT signaling pathway

Adult stem cells

Cancer stem cells

Secreted Protein

Nuclear Hormone Receptor

Stem cell relevant signaling - DSL/Notch pathway

Stem cell relevant signaling - Wnt Signaling pathway

Metabolic pathways

Pathways in cancer

Focal adhesion

MAPK signaling pathway

Regulation of actin cytoskeleton

Prostate cancer

Chemokine signaling pathway

Endocytosis

Chronic myeloid leukemia

Insulin signaling pathway

Endometrial cancer

Neurotrophin signaling pathway

Pancreatic cancer

ErbB signaling pathway

Colorectal cancer

Glioma

Melanoma

Non-small cell lung cancer

Small cell lung cancer

Bladder cancer

Natural killer cell mediated cytotoxicity

Wnt signaling pathway

Acute myeloid leukemia

Cytokine-cytokine receptor interaction

Fc gamma R-mediated phagocytosis

Renal cell carcinoma

Cell cycle

T cell receptor signaling pathway

Adherens junction

Leukocyte transendothelial migration

Cell adhesion molecules (CAMs)

Axon guidance

Tight junction

Ubiquitin mediated proteolysis

Apoptosis

p53 signaling pathway

Alzheimer's disease

Jak-STAT signaling pathway

Progesterone-mediated oocyte maturation

Thyroid cancer

Toll-like receptor signaling pathway

Fc epsilon RI signaling pathway

Oocyte meiosis

B cell receptor signaling pathway

Huntington's disease

Melanogenesis

Pathogenic Escherichia coli infection

TGF-beta signaling pathway

VEGF signaling pathway

Long-term potentiation

Hematopoietic cell lineage

Long-term depression

Neuroactive ligand-receptor interaction

GnRH signaling pathway

RIG-I-like receptor signaling pathway

Calcium signaling pathway

Gap junction

mTOR signaling pathway

Adipocytokine signaling pathway

PPAR signaling pathway

Glycolysis / Gluconeogenesis

Viral myocarditis

Amyotrophic lateral sclerosis (ALS)

Basal cell carcinoma

Lysosome

Spliceosome

Vascular smooth muscle contraction

NOD-like receptor signaling pathway

Antigen processing and presentation

Arrhythmogenic right ventricular cardiomyopathy (ARVC)

Cytosolic DNA-sensing pathway

ECM-receptor interaction

Epithelial cell signaling in Helicobacter pylori infection

Complement and coagulation cascades

Glutathione metabolism

Hypertrophic cardiomyopathy (HCM)

Prion diseases

Purine metabolism

Type I diabetes mellitus

Type II diabetes mellitus

Citrate cycle (TCA cycle)

Dilated cardiomyopathy

Metabolism of xenobiotics by cytochrome P450

Parkinson's disease

Dorso-ventral axis formation

Notch signaling pathway

Arginine and proline metabolism

DNA replication

Pyrimidine metabolism

Sphingolipid metabolism

Tryptophan metabolism

Valine

Vibrio cholerae infection

Arachidonic acid metabolism

Base excision repair

Butanoate metabolism

Cysteine and methionine metabolism

Drug metabolism - cytochrome P450

Fructose and mannose metabolism

Graft-versus-host disease

Inositol phosphate metabolism

Pyruvate metabolism

leucine and isoleucine degradation

Alanine

Hedgehog signaling pathway

Maturity onset diabetes of the young

Nucleotide excision repair

Phosphatidylinositol signaling system

Systemic lupus erythematosus

aspartate and glutamate metabolism

Autoimmune thyroid disease

Glycosaminoglycan degradation

Histidine metabolism

Other glycan degradation

Regulation of autophagy

Retinol metabolism

SNARE interactions in vesicular transport

Starch and sucrose metabolism

Allograft rejection

Amino sugar and nucleotide sugar metabolism

Glycerolipid metabolism

Glycerophospholipid metabolism

Homologous recombination

Lysine degradation

Nicotinate and nicotinamide metabolism

beta-Alanine metabolism

Androgen and estrogen metabolism

Cardiac muscle contraction

Drug metabolism - other enzymes

Fatty acid metabolism

Galactose metabolism

Linoleic acid metabolism

Non-homologous end-joining

Oxidative phosphorylation

Pentose phosphate pathway

Primary immunodeficiency

Renin-angiotensin system

Tyrosine metabolism

Aminoacyl-tRNA biosynthesis

Ascorbate and aldarate metabolism

C21-Steroid hormone metabolism

Ether lipid metabolism

Folate biosynthesis

Glycine

Glycosphingolipid biosynthesis - lacto and neolacto series

Mismatch repair

Phenylalanine metabolism

Porphyrin and chlorophyll metabolism

Propanoate metabolism

Proteasome

RNA degradation

serine and threonine metabolism

ABC transporters

Asthma

Biosynthesis of unsaturated fatty acids

Chondroitin sulfate biosynthesis

Glycosphingolipid biosynthesis - globo series

Glyoxylate and dicarboxylate metabolism

Limonene and pinene degradation

Nitrogen metabolism

Olfactory transduction

Pentose and glucuronate interconversions

Primary bile acid biosynthesis

Ribosome

Selenoamino acid metabolism

Synthesis and degradation of ketone bodies

Taurine and hypotaurine metabolism

Vitamin B6 metabolism

alpha-Linolenic acid metabolism

leucine and isoleucine biosynthesis

Basal transcription factors

Circadian rhythm - mammal

D-Glutamine and D-glutamate metabolism

Fatty acid elongation in mitochondria

Glycosphingolipid biosynthesis - ganglio series

Glycosylphosphatidylinositol(GPI)-anchor biosynthesis

Heparan sulfate biosynthesis

O-Glycan biosynthesis

O-Mannosyl glycan biosynthesis

One carbon pool by folate

Pantothenate and CoA biosynthesis

Protein export

Taste transduction

Terpenoid backbone biosynthesis

Thiamine metabolism

1

Yes

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